PBXIP1 Activators represent a specific subset of chemical compounds that have garnered attention in the field of molecular biology and cellular research. These activators are tailored to modulate the activity of the PBXIP1 gene, with PBXIP1 denoting Pre-B-Cell Leukemia Homeobox-Interacting Protein 1. This gene is a protein-coding element found in humans and is part of the PBX family of transcription factors. While the exact biological functions of PBXIP1 are still under investigation, it is believed to play a role in transcriptional regulation and gene expression, contributing to various cellular processes. PBXIP1 Activators are a category of molecules designed to enhance or stimulate the expression and function of the PBXIP1 gene, ultimately leading to an increase in the activity of the associated protein.
The mechanism of action of PBXIP1 Activators typically involves their interaction with specific regulatory elements within the PBXIP1 gene, such as its promoter or enhancer sequences. These interactions facilitate the upregulation of gene transcription, resulting in heightened synthesis of the PBXIP1 protein. The PBXIP1 protein is thought to be involved in protein-protein interactions with other transcription factors, potentially influencing the transcription of target genes. As researchers delve deeper into the functions and potential implications of PBXIP1 activation, the development and refinement of PBXIP1 Activators hold promise for advancing our understanding of gene regulation, transcriptional control, and the broader role of PBXIP1 in cellular biology, potentially shedding light on novel aspects of cellular processes and molecular pathways.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic acid, involved in cellular differentiation, might upregulate PBXIP1 as part of gene expression modulation during development and differentiation processes. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $71.00 $163.00 $296.00 | 2 | |
Vitamin D3, through its nuclear receptor, might influence PBXIP1 expression in cells involved in immune responses or bone metabolism. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin raises cAMP levels, potentially enhancing PBXIP1 expression through cAMP-responsive elements in its promoter region in cells responsive to cAMP signaling. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
This green tea polyphenol might modulate PBXIP1 expression through antioxidant response pathways or as part of its anti-cancer properties. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin's anti-inflammatory and anti-cancer effects might involve the upregulation of PBXIP1, potentially influencing pathways related to cell adhesion and migration. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
As a sirtuin activator, resveratrol might affect PBXIP1 expression as part of its role in cellular stress responses and aging. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
As a histone deacetylase inhibitor, sodium butyrate could increase chromatin accessibility, potentially leading to upregulated expression of PBXIP1. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $91.00 $139.00 $374.00 | 36 | |
This glucocorticoid might modulate PBXIP1 expression as part of its wide-ranging effects on immune response and inflammation. | ||||||
Hydroxyurea | 127-07-1 | sc-29061 sc-29061A | 5 g 25 g | $78.00 $260.00 | 18 | |
Hydroxyurea, through its role in inducing DNA damage response, might affect PBXIP1 expression as part of cellular stress responses. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
As an mTOR inhibitor, rapamycin might influence PBXIP1 expression in the context of cell growth, proliferation, and autophagy. | ||||||