Date published: 2026-4-24

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palladin Inhibitors

Palladin inhibitors are a class of chemical compounds that have garnered significant attention in the field of molecular biology and cellular research. These inhibitors target palladin, a protein that plays a pivotal role in cytoskeletal organization and cell motility. Palladin itself is an actin-associated protein, and it is primarily found in cells with dynamic cytoskeletal structures, such as muscle cells, fibroblasts, and neurons. The discovery of palladin inhibitors has opened up new avenues for studying the fundamental processes governing cell morphology, motility, and migration.

These inhibitors are designed to specifically interact with palladin, disrupting its normal functions within the cell. Palladin is known to regulate actin dynamics and act as a scaffold protein, contributing to the formation of cellular structures like stress fibers and focal adhesions. By inhibiting palladin, researchers can investigate its precise role in these processes and gain deeper insights into the molecular mechanisms that underlie cell shape changes and motility.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Y-27632, free base

146986-50-7sc-3536
sc-3536A
5 mg
50 mg
$186.00
$707.00
88
(1)

Inhibits ROCK kinase, which is involved in actin cytoskeleton remodeling, thus indirectly influencing palladin's function.

(S)-(−)-Blebbistatin

856925-71-8sc-204253
sc-204253A
sc-204253B
sc-204253C
1 mg
5 mg
10 mg
25 mg
$72.00
$265.00
$495.00
$968.00
(2)

Inhibits myosin II ATPase activity, affecting cell contractility and thereby influencing palladin's role in maintaining cell shape.

CK 666

442633-00-3sc-361151
sc-361151A
10 mg
50 mg
$321.00
$1040.00
5
(0)

Inhibits ARP2/3 complex-mediated actin nucleation, affecting the formation of branched actin networks where palladin may localize.

NVP-BHG712

940310-85-0sc-364554
sc-364554A
5 mg
50 mg
$232.00
$1764.00
(0)

Inhibits formin-mediated actin nucleation and elongation, affecting actin structures and potentially palladin's associated functions.

Wiskostatin

253449-04-6sc-204399
sc-204399A
sc-204399B
sc-204399C
1 mg
5 mg
25 mg
50 mg
$49.00
$124.00
$441.00
$828.00
4
(1)

Inhibits the N-WASP-Arp2/3 pathway, affecting actin polymerization and indirectly palladin's role in actin cytoskeleton organization.

Insulin

11061-68-0sc-29062
sc-29062A
sc-29062B
100 mg
1 g
10 g
$156.00
$1248.00
$12508.00
82
(1)

Stabilizes actin filaments in a state that is less favorable for branching and network formation, indirectly affecting palladin's role in actin dynamics.

Phalloidin

17466-45-4sc-202763
1 mg
$234.00
33
(1)

Binds and stabilizes actin filaments, affecting the dynamic turnover of the cytoskeleton and hence palladin's role in these processes.