The PABPC5 protein, or Poly(A) Binding Protein Cytoplasmic 5, is a member of the poly(A) binding protein family. These proteins are highly conserved across species and play critical roles in several stages of mRNA metabolism. They're encoded by the PABPC5 gene in humans.PABPs generally function by binding to the poly(A) tail of mRNA molecules, a structure found at the end of most eukaryotic mRNAs. This binding plays several crucial roles, such as promoting mRNA stability, facilitating mRNA export from the nucleus to the cytoplasm, and regulating translation initiation.
Like other PABPs, it's likely to be involved in similar mRNA metabolic processes and may have specific roles in certain tissues or at different developmental stages.Given the fundamental role of PABPs in mRNA metabolism, disruptions in their function results in a wide variety of diseases, including cancers, neurological disorders, and infectious diseases. Therefore, it is of significant interest to better understand the function and regulation of proteins like PABPC5.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Fluorouracil | 51-21-8 | sc-29060 sc-29060A | 1 g 5 g | $37.00 $152.00 | 11 | |
Affects RNA processing and could indirectly influence PABPC5's role in mRNA metabolism. | ||||||
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $41.00 $74.00 $221.00 $247.00 $738.00 $1220.00 | 39 | |
Stabilizes microtubules and can disrupt cell division, potentially influencing mRNA processing and PABPC5 activity indirectly. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
A histone deacetylase inhibitor, can alter gene expression, potentially impacting PABPC5's function indirectly. | ||||||
17-AAG | 75747-14-7 | sc-200641 sc-200641A | 1 mg 5 mg | $67.00 $156.00 | 16 | |
An HSP90 inhibitor, could affect various cellular processes, including those involving PABPC5. | ||||||