Date published: 2025-12-7

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PA26 Activators

The chemical class called SESN1 Activators includes compounds that can indirectly influence the activity of SESN1 through their effects on oxidative stress response, autophagy, and metabolic pathways. These compounds do not directly activate SESN1; instead, they create cellular conditions or modulate pathways that could enhance SESN1's functional role in responding to cellular stress.

Antioxidants like N-Acetylcysteine, Resveratrol, Curcumin, Sulforaphane, Quercetin, Alpha-Lipoic Acid, and Trolox could modulate oxidative stress pathways, potentially enhancing SESN1's role in these responses. Rapamycin and Spermidine, known for their effects on autophagy, might indirectly influence SESN1's activity in autophagic processes. Metformin and Berberine, by activating AMPK, could impact metabolic stress pathways relevant to SESN1. EGCG, with its broad spectrum of biological effects, might also indirectly impact pathways relevant to SESN1.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

α-Lipoic Acid

1077-28-7sc-202032
sc-202032A
sc-202032B
sc-202032C
sc-202032D
5 g
10 g
250 g
500 g
1 kg
$68.00
$120.00
$208.00
$373.00
$702.00
3
(1)

An antioxidant that could modulate cellular redox states, potentially impacting SESN1's activity.

Berberine

2086-83-1sc-507337
250 mg
$90.00
1
(0)

Has been shown to activate AMPK and influence metabolic regulation, potentially impacting SESN1.

Trolox

53188-07-1sc-200810
sc-200810A
sc-200810B
sc-200810C
sc-200810D
500 mg
1 g
5 g
25 g
100 g
$37.00
$66.00
$230.00
$665.00
$1678.00
39
(1)

A vitamin E analog, acts as an antioxidant, potentially influencing oxidative stress response pathways involving SESN1.

Spermidine

124-20-9sc-215900
sc-215900B
sc-215900A
1 g
25 g
5 g
$56.00
$595.00
$173.00
(2)

Known to induce autophagy, could have an indirect effect on SESN1's role in autophagic processes.