p38 beta Inhibitors
Santa Cruz Biotechnology now offers a broad range of p38 beta Inhibitors. MAP (mitogen-activated protein) kinases play a significant role in many biological processes, including cell adhesion and spreading, cell differentiation and apoptosis. p38α, p38β and p38γ, also known as MAPK14, MAPK11 and MAPK12, respectively. p38 beta Inhibitors offered by Santa Cruz inhibit p38 beta and, in some cases, other signal transduction and cell proliferation related proteins. View detailed p38 beta Inhibitor specifications, including p38 beta Inhibitor CAS number, molecular weight, molecular formula and chemical structure, by clicking on the product name.
Items 11 to 16 of 16 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
VX 702 | 745833-23-2 | sc-361400 | 10 mg | $135.00 | 1 | |
VX 702 is a potent inhibitor of p38 beta MAPK, distinguished by its selective binding affinity that disrupts ATP binding and alters the enzyme's active site conformation. This compound exhibits unique kinetic properties, leading to a pronounced effect on substrate recognition and phosphorylation rates. Its lipophilic nature facilitates membrane penetration, allowing for enhanced interactions with cellular components and modulation of signaling networks, thereby influencing various biological processes. | ||||||
SB 239063 | 193551-21-2 | sc-220094B sc-220094 sc-220094A | 500 µg 5 mg 25 mg | $119.00 $162.00 $645.00 | 7 | |
SB239063 is a selective p38 MAPK inhibitor, including p38β. By directly inhibiting p38β, SB239063 modulates its cellular functions, potentially affecting inflammation and stress response pathways. This direct inhibition provides a tool to study the specific role of p38β in cellular processes. | ||||||
Poly-ε-cbz-L-lysine | 25931-47-9 | sc-396758 | 1 g | $174.00 | ||
Poly-ε-cbz-L-lysine is a synthetic polymer characterized by its unique amino acid sequence, which facilitates specific interactions with biological macromolecules. Its structure allows for the formation of stable secondary structures, influencing molecular recognition processes. The polymer exhibits distinct solubility properties, enabling it to interact favorably in diverse environments. Additionally, its reactivity profile supports various modification strategies, enhancing its functional versatility in complex systems. | ||||||
SB202190 hydrochloride | 350228-36-3 | sc-222294 sc-222294A | 1 mg 5 mg | $131.00 $505.00 | 13 | |
SB202190 hydrochloride is a selective inhibitor of p38 MAP kinase, exhibiting unique binding affinity that disrupts specific phosphorylation pathways. Its structural conformation allows for precise interactions with the ATP-binding site, leading to altered reaction kinetics. The compound's hydrophilic nature enhances solubility in aqueous environments, facilitating its engagement in biochemical assays. Additionally, its ability to modulate protein-protein interactions underscores its role in cellular signaling dynamics. | ||||||
LY2228820 | 862507-23-1 | sc-364525 | 5 mg | $191.00 | 1 | |
LY2228820 is a potent and selective inhibitor of p38 MAPK, including p38β. By targeting the ATP-binding site, LY2228820 directly inhibits p38β, influencing its cellular functions. This direct inhibition may impact the regulation of inflammation and other processes associated with p38β activity. | ||||||
Losmapimod | 585543-15-3 | sc-489299 sc-489299A | 10 mg 50 mg | $228.00 $825.00 | ||
Losmapimod is a selective inhibitor of p38 MAP kinase, showcasing unique interactions with the enzyme's ATP-binding site. Its design allows for specific conformational changes in the kinase, influencing downstream signaling pathways involved in cellular stress responses. The compound's kinetic profile reveals a slow dissociation rate from the target, enhancing its efficacy. Additionally, Losmapimod's solubility characteristics facilitate its behavior in diverse biochemical environments, promoting stability and reactivity. | ||||||