SB202190 hydrochloride (CAS 350228-36-3)

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Alternate Names: 4-[4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]phenol Monohydrochloride

Application: SB202190 hydrochloride is an inhibitor of the isoforms p38α and p38&beta

CAS Number: 350228-36-3

Purity: ≥96%

Molecular Weight: 367.80

Molecular Formula: C₂₀H₁₄FN₃O•HCl

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

* Refer to Certificate of Analysis for lot specific data (including water content).

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SB202190 hydrochloride is a water soluble form of the potent p38 (SAPK2a) inhibitor SB202190 (sc-202334).

Physical State :

Solid

Storage :

Store at -20° C

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

PubChem CID :

6419751

SMILES :

C1=CC(=O)C=CC1=C2NC(=C(N2)C3=CC=NC=C3)C4=CC=C(C=C4)F.Cl

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Certificate of Analysis

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SB202190 hydrochloride (CAS 350228-36-3) Product Citations

See how others have used SB202190 hydrochloride (CAS 350228-36-3). Click on the entry to view the PubMed entry .

Citations 1 to 10 of 11 total

PMID: # 28747804 van der Linden, M. et al. 2017. Sci Rep. 7: 6529.

PMID: # 26699492 Olabisi, OA. et al. 2016. Proc. Natl. Acad. Sci. U.S.A. 113: 830-7.

PMID: # 25834401 Li, JP. et al. 2015. Drug Des Devel Ther. 9: 1627-52.

PMID: # 25638774 Abdalla, MY. et al. 2015. Redox Biol. 4: 328-39.

PMID: # 25197927 Zhang, M. et al. 2014. Cell Transplant. 23: 1061-73.

PMID: # 23457635 Fields, J. et al. 2013. PLoS ONE. 8: e56891.

PMID: # 23029125 Mamik, MK. et al. 2012. PLoS ONE. 7: e45596.

PMID: # 11295527 Anania, FA. et al. 2001. Free Radic. Biol. Med. 30: 846-57.

PMID: # 32703189 BMC Cancer. 685.

Citations 1 to 10 of 11 total

Rated 5 out of 5 by SS from Gardner Gardner, S. et al. (PubMed 26246429) used SB202190, a p38 inhibitor, to demonstrate that activity of p38 / is important not only for the early phases of myoblast differentiation, but also later stages of myocyte fusion and myofibrillogenesis. -SCBT Publication Review

Date published: 2015-04-15

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