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SB202190 hydrochloride (CAS 350228-36-3)
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Synonym:
4-[4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]phenol Monohydrochloride
Application:
An inhibitor of the isoforms p38α and p38&beta
CAS Number:
350228-36-3
Purity:
≥96%
Molecular Weight:
367.80
Molecular Formula:
C20H14FN3O•HCl
* Refer to Certificate of Analysis for lot specific data (including water content).
SB202190 hydrochloride is a water soluble form of the potent p38 (SAPK2a) inhibitor SB202190 (sc-202334).
Physical State
:
Solid
Storage
:
Store at -20° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID
:
6419751
SMILES
:
C1=CC(=O)C=CC1=C2NC(=C(N2)C3=CC=NC=C3)C4=CC=C(C=C4)F.Cl
Download SDS (MSDS)
Certificate of Analysis
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SB202190 hydrochloride Product Citations
See how others have used SB202190 hydrochloride. Click on the entry to view the PubMed entry .
PMID: # 28396222 Zhang, L.|Xu, P.|Wang, X.|Zhang, M.|Yan, Y.|Chen, Y.|Zhang, L.|Zhang, L.| et al. 2017. Int. J. Biochem. Cell Biol. 87: 69-76.
PMID: # 28747804 van der Linden, M. et al. 2017. Sci Rep. 7: 6529.
PMID: # 26699492 Olabisi, OA. et al. 2016. Proc. Natl. Acad. Sci. U.S.A. 113: 830-7.
PMID: # 25834401 Li, JP. et al. 2015. Drug Des Devel Ther. 9: 1627-52.
PMID: # 25638774 Abdalla, MY. et al. 2015. Redox Biol. 4: 328-39.
PMID: # 25197927 Zhang, M. et al. 2014. Cell Transplant. 23: 1061-73.
PMID: # 23457635 Fields, J. et al. 2013. PLoS ONE. 8: e56891.
PMID: # 23029125 Mamik, MK. et al. 2012. PLoS ONE. 7: e45596.
PMID: # 11295527 Anania, FA. et al. 2001. Free Radic. Biol. Med. 30: 846-57.
Rated 5 out of
5
by
SS from
Gardner
Gardner, S. et al. (PubMed 26246429) used SB202190, a p38 inhibitor, to demonstrate that activity of p38 / is important not only for the early phases of myoblast differentiation, but also later stages of myocyte fusion and myofibrillogenesis. -SCBT Publication Review
Date published: 2015-04-15
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