Date published: 2026-4-5

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P2X7 Antibodies

Santa Cruz Biotechnology offers a broad range of P2X7 monoclonal antibodies for research focused on understanding P2X7 receptor functions. P2X7 monoclonal antibodies are compatible with multiple experimental applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). The P2X7 receptor is a crucial component of the purinergic signaling pathway, playing a significant role in immune responses and inflammation. P2X7 receptors mediate the release of pro-inflammatory cytokines and are implicated in various pathological conditions, including chronic pain, neurodegenerative diseases, and cancer. Understanding P2X7 receptor function is essential for developing targeted therapies and advancing knowledge of cellular communication. Researchers worldwide utilize P2X7 monoclonal antibodies to investigate receptor distribution across different tissues and cell types. Advanced visualization techniques with P2X7 monoclonal antibodies enable detailed examination of receptor localization and trafficking within cells. Multiple conjugation options, including horseradish peroxidase (HRP), phycoerythrin (PE), and fluorescein isothiocyanate (FITC), provide flexibility in experimental design. Santa Cruz Biotechnology monoclonal antibodies for P2X7 research contribute to advancing scientific understanding of cellular signaling pathways and potential therapeutic targets.

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P2X7 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

P2X7 Antibody (D-1)

sc-514962mouse IgG2a κ81-106 (h)WB, IP, IF, ELISAm, r, h
27
(12)

P2X7 Antibody (Hano43)

sc-134224rat IgG2bFL (m)WB, IP, IF, FCMm, r
5
(1)

P2X7 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

P2X7 CRISPR/Cas9 KO Plasmid (h)

sc-400780hGene KnockoutGFP0
(0)

P2X7 HDR Plasmid (h)

sc-400780-HDRhHomology Directed RepairPuromycin0
(0)

P2X7 Double Nickase Plasmid (h)

sc-400780-NIChGene KnockoutPuromycin0
(0)

P2X7 Double Nickase Plasmid (h2)

sc-400780-NIC-2hGene KnockoutPuromycin0
(0)

P2X7 CRISPR/Cas9 KO Plasmid (m)

sc-422093mGene KnockoutGFP
1
(0)

P2X7 HDR Plasmid (m)

sc-422093-HDRmHomology Directed RepairPuromycin
1
(0)

P2X7 Double Nickase Plasmid (m)

sc-422093-NICmGene KnockoutPuromycin
1
(0)

P2X7 Double Nickase Plasmid (m2)

sc-422093-NIC-2mGene KnockoutPuromycin
1
(0)

P2X7 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

P2X7 CRISPR Activation Plasmid (h)

sc-400780-ACThGene ActivationPuro, Blast, Hygro0
(0)

P2X7 CRISPR Activation Plasmid (h2)

sc-400780-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

P2X7 Lentiviral Activation Particles (h2)

sc-400780-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

P2X7 CRISPR Activation Plasmid (m)

sc-422093-ACTmGene ActivationPuro, Blast, Hygro
1
(0)

P2X7 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

P2X shRNA Plasmid (r)

sc-108056-SHrGene SilencingPuromycin
4
(0)

P2X shRNA (r) Lentiviral Particles

sc-108056-VrGene SilencingPuromycin
4
(0)

P2X7 siRNA (h)

sc-42575hGene SilencingN/A
12
(0)

P2X7 shRNA Plasmid (h)

sc-42575-SHhGene SilencingPuromycin
12
(0)

P2X7 shRNA (h) Lentiviral Particles

sc-42575-VhGene SilencingPuromycin
12
(0)

P2X7 siRNA (m)

sc-42576mGene SilencingN/A
9
(0)

P2X7 shRNA Plasmid (m)

sc-42576-SHmGene SilencingPuromycin
9
(0)

P2X7 shRNA (m) Lentiviral Particles

sc-42576-VmGene SilencingPuromycin
9
(0)

P2X7 siRNA (r)

sc-108056rGene SilencingN/A
4
(0)