Date published: 2026-2-2

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p21 Activators

Santa Cruz Biotechnology now offers a broad range of p21 Activators for use in various applications. p21 Activators target the cyclin-dependent kinase inhibitor p21, a crucial regulatory protein involved in cell cycle control and apoptosis. By activating p21, researchers can delve into the complex mechanisms that regulate cell cycle progression, particularly the transitions between different phases of the cell cycle. These activators are essential tools for studying the intricate signaling pathways that govern cellular responses to DNA damage, stress, and other regulatory signals. p21 Activators provide valuable insights into the role of p21 in maintaining genomic stability, as well as its function in cell cycle arrest and senescence. Utilizing p21 Activators allows scientists to explore how p21 interacts with other cell cycle regulators and its impact on the modulation of cyclin-dependent kinases. This facilitates a deeper understanding of the molecular mechanisms that underpin cell cycle checkpoints and the maintenance of cellular homeostasis. Moreover, p21 Activators are particularly useful in research focused on the interplay between cell cycle regulation and various cellular processes, including differentiation and apoptosis. By leveraging p21 Activators, researchers can investigate the dynamic processes that control cell proliferation and survival, providing critical insights into fundamental biological processes. View detailed information on our available p21 Activators by clicking on the product name.

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Items 11 to 13 of 13 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

5-Azacytidine

320-67-2sc-221003
500 mg
$280.00
4
(1)

5-azacytidine, a DNA demethylating agent, can reactivate silenced p21 gene expression by reversing DNA methylation, restoring its normal regulatory function.

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$152.00
$479.00
$632.00
$1223.00
$2132.00
33
(3)

Trichostatin A is an HDAC inhibitor that activates p21 by preventing histone deacetylation, leading to increased p21 expression and cell cycle arrest.

Suberoylanilide Hydroxamic Acid

149647-78-9sc-220139
sc-220139A
100 mg
500 mg
$133.00
$275.00
37
(2)

Vorinostat, another HDAC inhibitor, activates p21 by inhibiting HDAC enzymes, promoting histone acetylation, and subsequently upregulating p21 expression.