Date published: 2025-10-17

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Other Crosslinkers

Santa Cruz Biotechnology now offers a broad range of Crosslinkers for use in various applications. Crosslinkers are pivotal in scientific research as they enable the covalent bonding of molecules to study protein interactions, molecular structures, and biochemical pathways. These reagents facilitate the linking of two or more molecules, such as proteins or nucleic acids, which helps in stabilizing complex structures and understanding the spatial arrangement of biological macromolecules. The Other Crosslinkers category encompasses a diverse array of chemical entities designed to create specific and stable covalent bonds between target molecules under various experimental conditions. These compounds are essential in studying protein-protein interactions, mapping binding sites, and elucidating the architecture of macromolecular complexes. By employing these crosslinkers, researchers can capture transient interactions and stabilize delicate structures for analysis using techniques such as mass spectrometry, X-ray crystallography, and nuclear magnetic resonance (NMR) spectroscopy. Furthermore, crosslinkers are instrumental in the development of new materials, as they are used to modify surface properties, create hydrogels, and improve the mechanical strength of polymers. The versatility and specificity of Other Crosslinkers make them invaluable tools for advancing research in structural biology, biochemistry, and materials science. View detailed information on our available Other Crosslinkers by clicking on the product name.

Items 161 to 170 of 214 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Ramage-Linker

212783-75-0sc-296257
sc-296257A
5 g
25 g
$165.00
$928.00
(0)

Ramage-Linker is a versatile crosslinker distinguished by its unique reactivity as an acid halide, enabling rapid formation of covalent bonds with nucleophiles. Its specific molecular architecture allows for selective interactions, enhancing the stability of crosslinked structures. The compound's reaction kinetics are notably efficient, promoting swift network formation. Additionally, its physical properties, such as solubility and compatibility with diverse materials, contribute to its effectiveness in creating durable polymer matrices.

5-(4-Hydroxymethyl-3-methoxyphenoxy)valeric acid

213024-57-8sc-233171
1 g
$93.00
(0)

5-(4-Hydroxymethyl-3-methoxyphenoxy)valeric acid serves as a distinctive crosslinker, characterized by its ability to engage in dynamic hydrogen bonding and π-π stacking interactions. This compound exhibits a unique reactivity profile, facilitating the formation of robust networks through its functional groups. Its moderate polarity enhances solubility in various solvents, promoting effective dispersion in polymer systems. The compound's structural features enable tailored crosslinking pathways, optimizing mechanical properties in composite materials.

N-Boc-4-isothiocyanatobutylamine

247035-47-8sc-228681
1 ml
$191.00
(0)

N-Boc-4-isothiocyanatobutylamine functions as a versatile crosslinker, notable for its ability to form thiourea linkages through nucleophilic attack on isothiocyanate groups. This compound exhibits rapid reaction kinetics, allowing for efficient network formation. Its hydrophobic characteristics contribute to enhanced compatibility with non-polar matrices, while the Boc protecting group provides stability during processing. The unique reactivity enables precise control over crosslink density, influencing the material's thermal and mechanical properties.

N-Dihydrocinnamoylaminocaproic Acid, N-Hydroxysuccinimide Ester

334616-48-7sc-219147
10 mg
$300.00
(0)

N-Dihydrocinnamoylaminocaproic Acid, N-Hydroxysuccinimide Ester serves as an effective crosslinker, distinguished by its ability to engage in amide bond formation through nucleophilic acyl substitution. This compound showcases a unique reactivity profile, facilitating selective crosslinking in diverse environments. Its hydrophilic nature enhances solubility in aqueous systems, while the presence of the hydroxysuccinimide moiety promotes efficient conjugation with primary amines, allowing for tailored network architectures.

2-[2-(Boc-amino)ethoxy]ethoxyacetic acid (dicyclohexylammonium) salt

560088-79-1sc-287660
500 mg
$262.00
(0)

2-[2-(Boc-amino)ethoxy]ethoxyacetic acid (dicyclohexylammonium) salt functions as a versatile crosslinker, characterized by its ability to form stable ester bonds through its carboxylic acid functionality. The Boc-protected amine group enhances its reactivity, enabling selective interactions with various nucleophiles. Its unique ether linkages contribute to increased flexibility and solubility in organic solvents, facilitating the formation of robust polymer networks with tailored mechanical properties.

N-(3-Trifluoroethanesulfonyloxypropyl)anthraquinone-2-carboxamide

661461-84-3sc-218940
25 mg
$300.00
(0)

N-(3-Trifluoroethanesulfonyloxypropyl)anthraquinone-2-carboxamide serves as a distinctive crosslinker, notable for its ability to engage in strong hydrogen bonding and π-π stacking interactions due to its anthraquinone structure. The trifluoroethanesulfonyloxy group enhances electrophilicity, promoting rapid reaction kinetics with nucleophiles. Its unique molecular architecture allows for the formation of highly stable crosslinked networks, contributing to improved thermal stability and mechanical integrity in polymer systems.

O6-[4-(Trifluoroacetamidomethyl)benzyl]guanine

680622-70-2sc-219457
1 mg
$330.00
(0)

O6-[4-(Trifluoroacetamidomethyl)benzyl]guanine acts as a versatile crosslinker, characterized by its ability to form covalent bonds through its guanine moiety. The trifluoroacetamidomethyl group introduces significant steric hindrance, influencing reaction selectivity and kinetics. This compound exhibits unique interactions with nucleophiles, facilitating the formation of robust crosslinked structures that enhance material resilience and stability under varying conditions. Its distinct molecular design allows for tailored reactivity in complex systems.

16-Methanethiosulfonyl Hexadecanoic Acid

887406-81-7sc-213617
10 mg
$360.00
(0)

16-Methanethiosulfonyl Hexadecanoic Acid serves as an effective crosslinker, distinguished by its unique thiosulfonyl group that promotes selective covalent bonding with thiol-containing compounds. This feature enhances the formation of stable crosslinked networks, improving mechanical properties and thermal stability. The long hydrophobic hexadecanoic chain contributes to increased compatibility with lipid membranes, facilitating specific interactions in diverse environments. Its reactivity profile allows for controlled crosslinking in complex matrices.

[N-(2-Maleimidoethyl]ethylenediamine-N,N,N′,N′-tetraacetic Acid, Monoamide

1185102-85-5sc-218919
10 mg
$360.00
(0)

N-(2-Maleimidoethyl)ethylenediamine-N,N,N',N'-tetraacetic Acid, Monoamide acts as a versatile crosslinker, characterized by its maleimide functionality that enables rapid and selective conjugation with thiol groups. This specificity facilitates the formation of robust, covalent linkages, enhancing structural integrity in polymer networks. Its chelating properties also allow for metal ion coordination, influencing reaction kinetics and stability in various chemical environments, making it suitable for diverse applications.

DBCO-maleimide

sc-397264
sc-397264A
1 mg
5 mg
$17.00
$81.00
(0)

DBCO-maleimide is a highly reactive crosslinker distinguished by its unique strain-promoted azide-alkyne cycloaddition (SPAAC) capability. This compound features a dibenzocyclooctyne (DBCO) moiety that engages in rapid, bioorthogonal reactions with azides, resulting in stable covalent bonds. Its exceptional reaction kinetics and selectivity make it ideal for creating complex networks, while its hydrophobic characteristics enhance compatibility with various substrates, promoting effective crosslinking in diverse systems.