OTC Activators
OTC activators, as identified in this list, are primarily compounds that can potentially enhance OTC activity indirectly by influencing the urea cycle or related metabolic pathways. These compounds do not directly activate OTC but affect the cellular environment and metabolic pathways that are crucial for its function. N-Acetylglutamate is the most directly relevant compound, serving as an essential allosteric activator of OTC by increasing its affinity for substrates. Substrates of the urea cycle, such as L-Ornithine, L-Arginine, L-Citrulline, and Carbamoyl phosphate, could enhance OTC activity by increasing the availability of substrates or modulating the cycle's flux.
Biotin, involved in carboxylase reactions, and Vitamin B6, essential for amino acid metabolism, might indirectly influence OTC activity by affecting overall metabolic processes. Compounds like Arginine Aspartate and Ornithine Aspartate provide precursors or substrates for the urea cycle, potentially enhancing OTC activity. Zinc supplements could have an indirect effect on OTC, given the importance of zinc in enzyme structure and function. Alpha-ketoglutarate, a key intermediate in the Krebs cycle, might indirectly influence OTC by impacting amino acid and nitrogen metabolism.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
N-Acetyl-L-glutamic acid | 1188-37-0 | sc-228659 | 25 g | $72.00 | ||
N-Acetylglutamate is an essential cofactor for OTC, enhancing its activity by increasing its affinity for substrates. | ||||||
Ornithine | 70-26-8 | sc-507552 | 100 mg | $77.00 | ||
L-Ornithine, a substrate for OTC, could potentially enhance its activity by increasing substrate availability. | ||||||
L-Arginine | 74-79-3 | sc-391657B sc-391657 sc-391657A sc-391657C sc-391657D | 5 g 25 g 100 g 500 g 1 kg | $20.00 $31.00 $61.00 $219.00 $352.00 | 2 | |
L-Arginine, involved in the urea cycle, could indirectly boost OTC activity by modulating overall cycle flux. | ||||||
L-Citrulline | 372-75-8 | sc-204784 sc-204784A | 25 g 200 g | $32.00 $240.00 | ||
L-Citrulline, part of the urea cycle, might influence OTC activity indirectly by affecting the balance of cycle intermediates. | ||||||
D-(+)-Biotin | 58-85-5 | sc-204706 sc-204706A sc-204706B | 1 g 5 g 25 g | $41.00 $107.00 $333.00 | 1 | |
Biotin, a cofactor for carboxylases, could indirectly affect OTC by influencing overall amino acid metabolism and urea cycle function. | ||||||
L-Glutamic Acid | 56-86-0 | sc-394004 sc-394004A | 10 g 100 g | $297.00 $577.00 | ||
L-Glutamate is involved in amino acid metabolism and could indirectly influence OTC activity. | ||||||
L-Ornithine L-aspartate salt | 3230-94-2 | sc-353656 | 100 g | $190.00 | ||
Ornithine Aspartate provides ornithine, potentially increasing OTC activity through increased substrate availability. | ||||||
α-Ketoglutaric Acid | 328-50-7 | sc-208504 sc-208504A sc-208504B sc-208504C sc-208504D sc-208504E sc-208504F | 25 g 100 g 250 g 500 g 1 kg 5 kg 16 kg | $33.00 $43.00 $63.00 $110.00 $188.00 $738.00 $2091.00 | 2 | |
Alpha-ketoglutarate, involved in the Krebs cycle, might indirectly influence OTC by affecting overall amino acid and nitrogen metabolism. | ||||||