L-Citrulline (CAS 372-75-8)
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L-Citrulline is an amino acid that is used in research related to the urea cycle and nitric oxide synthesis. It is a key compound in studies aimed at understanding the enzymatic pathways involved in the conversion of ammonia to urea, which is for the removal of toxic ammonia from the body. In biochemical research, L-Citrulline serves as a tool to explore the regulation of nitric oxide production, a molecule involved in various physiological processes, including vasodilation and immune response. Additionally, it is utilized in the study of amino acid transport and metabolism, as its levels can be indicative of the functioning of other related amino acids such as L-arginine. Research on L-Citrulline also extends to agricultural studies, where it is examined for its role in plant nitrogen metabolism and its effects on crop yield and stress resistance.
L-Citrulline (CAS 372-75-8) References
- Oral L-citrulline supplementation improves erection hardness in men with mild erectile dysfunction. | Cormio, L., et al. 2011. Urology. 77: 119-22. PMID: 21195829
- L-citrulline provides a novel strategy for treating chronic pulmonary hypertension in newborn infants. | Fike, CD., et al. 2014. Acta Paediatr. 103: 1019-26. PMID: 24862864
- Influence of L-citrulline and watermelon supplementation on vascular function and exercise performance. | Figueroa, A., et al. 2017. Curr Opin Clin Nutr Metab Care. 20: 92-98. PMID: 27749691
- The Effects of Oral l-Arginine and l-Citrulline Supplementation on Blood Pressure. | Khalaf, D., et al. 2019. Nutrients. 11: PMID: 31336573
- [The effect of supplementation with L-arginine and L-citrulline on physical performance: a systematic review]. | Huerta Ojeda, Á., et al. 2019. Nutr Hosp. 36: 1389-1402. PMID: 31682459
- l-Citrulline supplementation improves glucose and exercise tolerance in obese male mice. | Eshreif, A., et al. 2020. Exp Physiol. 105: 270-281. PMID: 31802553
- Therapeutic Potential of Citrulline as an Arginine Supplement: A Clinical Pharmacology Review. | Rashid, J., et al. 2020. Paediatr Drugs. 22: 279-293. PMID: 32140997
- The Effects of L-Citrulline on Blood-Lactate Removal Kinetics Following Maximal-Effort Exercise. | Divito, B., et al. 2022. J Diet Suppl. 19: 704-716. PMID: 34013839
- Watermelon and L-Citrulline in Cardio-Metabolic Health: Review of the Evidence 2000-2020. | Burton-Freeman, B., et al. 2021. Curr Atheroscler Rep. 23: 81. PMID: 34894302
- l-Citrulline ameliorates pathophysiology in a rat model of superimposed preeclampsia. | Man, AWC., et al. 2022. Br J Pharmacol. 179: 3007-3023. PMID: 34935131
- Antitumor Effects of L-citrulline on Hela Cervical Cancer Cell Lines. | Eren, CY., et al. 2022. Anticancer Agents Med Chem. 22: 3157-3162. PMID: 35473537
- L-Citrulline Supplementation Restrains Ferritinophagy-Mediated Ferroptosis to Alleviate Iron Overload-Induced Thymus Oxidative Damage and Immune Dysfunction. | Ba, T., et al. 2022. Nutrients. 14: PMID: 36364817
- Metabolic effects of L-citrulline in type 2 diabetes. | Bagheripour, F., et al. 2023. Acta Physiol (Oxf). 237: e13937. PMID: 36645144
- L-Citrulline: A novel hypothermic amino acid promoting thermotolerance in heat-exposed chickens. | Chowdhury, VS. 2023. Anim Sci J. 94: e13826. PMID: 36938778
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
L-Citrulline, 25 g | sc-204784 | 25 g | $32.00 | |||
L-Citrulline, 200 g | sc-204784A | 200 g | $240.00 | |||
| US: (Out of Stock: Availability March 13, 2026) | ||||||