OR6C1 Activators
Chemical activators of OR6C1 include a variety of compounds that engage with the olfactory receptor in ways that facilitate its functional activation. Anethole, for instance, binds to specific sites within OR6C1, inducing a conformational change that activates the G-protein coupled receptor (GPCR) pathway, setting off a series of intracellular signals. Similarly, isoamyl acetate and benzaldehyde activate OR6C1 by interacting with the receptor's ligand-binding domain, which triggers G-protein-mediated signal transduction that culminates in the activation of the receptor. Cinnamaldehyde and eucalyptol also function in this manner, by binding to OR6C1 and inducing a shape change that initiates G-protein signaling cascades, effectively switching the receptor from an inactive to an active state.
Further, compounds such as geraniol, methyl anthranilate, and vanillin bind to the ligand recognition sites on OR6C1, promoting conformational changes that activate the G-protein coupled receptor signaling pathway. Citral and ethyl vanillin engage OR6C1 through direct binding, leading to the activation of the receptor's G-protein signaling cascade and consequent functional activation. Likewise, limonene activates OR6C1 by interacting with specific binding sites, inducing a conformational change and activating the associated G-protein coupled signaling pathway. Lastly, alpha-pinene activates OR6C1 by binding to the receptor's ligand-binding domain, initiating the G-protein signaling cascade that is essential for the receptor's functional activation. Each of these chemicals activates OR6C1 by directly interacting with the receptor, leading to a series of biochemical events that transition OR6C1 from a resting state to one of activation without relying on increasing the expression level of the receptor or merely modulating its activity.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Anethole | 104-46-1 | sc-481571A sc-481571 | 10 g 100 g | $576.00 $316.00 | ||
Anethole activates OR6C1 by binding to specific sites within the receptor, which triggers a conformational change resulting in the activation of the G-protein coupled receptor (GPCR) pathway, leading to a cascade of intracellular signaling. | ||||||
Isopentyl acetate | 123-92-2 | sc-250190 sc-250190A | 100 ml 500 ml | $107.00 $225.00 | ||
Isoamyl acetate can activate OR6C1 through direct interaction with the receptor's ligand-binding domain, which promotes GPCR-mediated signal transduction, culminating in the receptor's functional activation. | ||||||
Cinnamic Aldehyde | 104-55-2 | sc-294033 sc-294033A | 100 g 500 g | $104.00 $228.00 | ||
Cinnamaldehyde can activate OR6C1 by directly binding to the receptor, which induces a shape change and initiates G-protein signaling cascades, resulting in the receptor's functional activation. | ||||||
1,8-Cineole | 470-82-6 | sc-485261 | 25 ml | $44.00 | 2 | |
Eucalyptol engages with OR6C1 at specific sites, causing a conformational shift that activates G-protein signaling pathways associated with the receptor, leading to its functional activation. | ||||||
Geraniol | 106-24-1 | sc-235242 sc-235242A | 25 g 100 g | $45.00 $119.00 | ||
Geraniol can activate OR6C1 by specifically interacting with the binding sites on the receptor, which triggers activation of the associated G-protein signaling mechanisms, resulting in receptor activation. | ||||||
Vanillin | 121-33-5 | sc-251423 sc-251423A | 100 g 500 g | $44.00 $124.00 | 1 | |
Vanillin can activate OR6C1 by binding to its ligand recognition sites, promoting a change in the receptor's conformation and activating the G-protein coupled receptor signaling pathway necessary for receptor activation. | ||||||
Citral | 5392-40-5 | sc-252620 | 1 kg | $212.00 | ||
Citral engages OR6C1 through direct binding, which leads to the activation of the receptor's G-protein signaling cascade, resulting in functional activation. | ||||||
3-Ethoxy-4-hydroxybenzaldehyde | 121-32-4 | sc-238538 | 100 g | $31.00 | ||
3-Ethoxy-4-hydroxybenzaldehyde activates OR6C1 by specifically binding to the receptor and inducing a conformational change that triggers the associated G-protein signaling pathway, leading to the receptor's functional activation. | ||||||
D-Limonene | 5989-27-5 | sc-205283 sc-205283A | 100 ml 500 ml | $84.00 $129.00 | 3 | |
Limonene activates OR6C1 by interacting with specific binding sites on the receptor, causing a conformational change that leads to the activation of the G-protein coupled signaling pathway, thereby activating the receptor. | ||||||
(−)-α-Pinene | 7785-26-4 | sc-239166 | 25 g | $43.00 | ||
Alpha-Pinene can activate OR6C1 as it binds to the receptor's ligand-binding domain, which then initiates the G-protein signaling cascade essential for the receptor's functional activation. | ||||||