OR5AK2 include a variety of compounds commonly found in essential oils and fragrances. Citral, a major component in lemongrass oil, engages OR5AK2 by docking to its ligand-binding site, triggering a series of intracellular reactions starting with a signal transduction cascade. Similarly, eugenol, which is found in clove oil, targets the receptor's binding domain, activating OR5AK2 and promoting a cellular response through associated G-proteins. Geraniol, another floral scent from rose oil and citronella, interacts with the sensory domain of OR5AK2, initiating G-protein-mediated signaling pathways. Methyl salicylate, known for its minty scent reminiscent of wintergreen, also participates in the activation of OR5AK2 by fitting snugly into the receptor's pocket, prompting a conformational change that propagates the signal through G-protein coupling.
OR5AK2, benzyl acetate, with its sweet floral aroma, binds to the receptor's active site, ensuing G-protein activation and the cascade of intracellular signaling. Isoamyl acetate, with its distinctive banana-like scent, engages OR5AK2 at its olfactory receptor site, leading to the activation of downstream signaling events. Limonene, found in citrus peels, and linalool, present in lavender and coriander, both activate OR5AK2 by binding to its ligand-binding domain, causing a change in receptor structure that triggers G-protein signaling. Similarly, alpha-ionone and beta-ionone, which emit violet-like scents, activate OR5AK2 by interacting with the active site of the receptor, inducing a series of signaling events inside the cell. Hexyl acetate adds to this list with its fruity fragrance, activating OR5AK2 by binding to the receptor's ligand-binding site, while alpha-terpineol, which offers a lilac scent, also activates the receptor, signaling through G-protein activation and subsequent intracellular pathways.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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Citral | 5392-40-5 | sc-252620 | 1 kg | $212.00 | ||
Citral is a component of lemongrass oil and activates olfactory receptors, which could include OR5AK2. By binding directly to the ligand-binding site of this olfactory receptor, citral triggers a signal transduction cascade leading to activation. | ||||||
Eugenol | 97-53-0 | sc-203043 sc-203043A sc-203043B | 1 g 100 g 500 g | $31.00 $61.00 $214.00 | 2 | |
Eugenol, found in clove oil, is known to activate olfactory receptors. It can activate OR5AK2 by interacting with the receptor's specific binding domain, initiating a cellular response via associated G-proteins. | ||||||
Geraniol | 106-24-1 | sc-235242 sc-235242A | 25 g 100 g | $44.00 $117.00 | ||
Geraniol, present in rose oil and citronella, is another olfactory receptor activator. It could activate OR5AK2 by binding to its sensory domain, promoting G-protein-mediated signaling pathways. | ||||||
Methyl Salicylate | 119-36-8 | sc-204802 sc-204802A | 250 ml 500 ml | $46.00 $69.00 | ||
Methyl salicylate, a wintergreen scent compound, can activate OR5AK2 by binding to its receptor pocket, which would initiate a conformational change and signal transduction through G-protein coupling. | ||||||
Benzyl acetate | 140-11-4 | sc-252427 | 100 g | $29.00 | 1 | |
Benzyl acetate, a floral scent compound, may activate OR5AK2 by binding to the olfactory receptor's active site, triggering G-protein activation and subsequent intracellular signaling cascades. | ||||||
Isopentyl acetate | 123-92-2 | sc-250190 sc-250190A | 100 ml 500 ml | $105.00 $221.00 | ||
Isoamyl acetate, known for its banana-like scent, could activate OR5AK2 by binding to its olfactory receptor site, leading to activation of G-proteins and a series of downstream signaling events. | ||||||
D-Limonene | 5989-27-5 | sc-205283 sc-205283A | 100 ml 500 ml | $82.00 $126.00 | 3 | |
Limonene, a citrus scent compound, can activate OR5AK2 by specifically binding to its ligand-binding domain, causing a receptor conformational change that activates G-protein signaling. | ||||||
Linalool | 78-70-6 | sc-250250 sc-250250A sc-250250B | 5 g 100 g 500 g | $46.00 $71.00 $108.00 | ||
Linalool, a component of lavender and coriander, may activate OR5AK2 by specifically interacting with its receptor site, leading to the activation of G-proteins and subsequent signaling pathways. | ||||||
α-Ionone | 127-41-3 | sc-239157 | 100 g | $75.00 | ||
Alpha-ionone, which has a violet-like scent, could activate OR5AK2 by binding to the olfactory receptor and causing a conformational change, resulting in G-protein activation and signal transduction. | ||||||
beta-Ionone | 14901-07-6 | sc-291976 | 25 ml | $83.00 | ||
Beta-ionone, similar to alpha-ionone, may activate OR5AK2 by binding to the receptor's active site, leading to G-protein-mediated intracellular signaling events. |