OR51L1 Activators
OR51L1 include a variety of compounds that can bind to and alter the conformation of this olfactory receptor, leading to the initiation of signal transduction. Benzaldehyde, with its structural similarity to known odorants that activate related olfactory receptors, can bind to the odorant binding site of OR51L1, inducing a conformational change that activates the receptor. Ethanol, on the other hand, diffuses through the olfactory epithelium and interacts with the hydrophobic cavity of OR51L1, leading to the activation of G-protein signaling cascades associated with olfactory transduction. Likewise, acetophenone, a fragrant ketone, fits into the binding site of OR51L1 and induces a receptor shape change, which activates the G-protein coupled response. Eugenol, being a volatile phenolic compound, can also bind to OR51L1, causing a conformational shift and initiating G-protein signal transduction.
OR51L1 are citronellal and limonene, both of which are terpenoids that interact with the ligand-binding domain of the receptor. Citronellal triggers a conformational alteration that activates the receptor and its associated G-protein pathway, while limonene's structure allows it to bind to OR51L1, causing a structural change and activating the olfactory signaling pathway. Anisaldehyde and vanillin, similar to the other chemical activators, bind to the ligand-binding domain of OR51L1, inducing receptor activation and the subsequent signaling processes. Phenylethyl alcohol, a floral scent compound, and hexanal can also activate OR51L1 through their structure's compatibility with the binding sites on the receptor, thus causing an activation of the receptor and the signaling mechanism. Lastly, geraniol and alpha-ionone are monoterpenoid and cyclic terpenoid, respectively, that activate OR51L1 by mimicking natural odorants, fitting snugly within the receptor's active site, and inducing a conformational change leading to receptor activation and the initiation of its signaling pathways.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Acetophenone | 98-86-2 | sc-239189 | 5 g | $20.00 | ||
Acetophenone, being a fragrant ketone, can activate OR51L1 by fitting into the receptor's binding site and inducing a shape change, which activates the receptor and initiates a G-protein coupled response. | ||||||
Eugenol | 97-53-0 | sc-203043 sc-203043A sc-203043B | 1 g 100 g 500 g | $32.00 $62.00 $218.00 | 2 | |
Eugenol activates OR51L1 as it is a volatile phenolic compound that can bind to olfactory receptors, causing a conformational shift that activates the receptor, leading to olfactory G-protein signal transduction. | ||||||
(±)-Citronellal | 106-23-0 | sc-234400 | 100 ml | $51.00 | ||
Citronellal, as a terpenoid, activates OR51L1 by interacting with the ligand-binding domain of the receptor, triggering a conformational alteration that activates the receptor and its associated G-protein pathway. | ||||||
D-Limonene | 5989-27-5 | sc-205283 sc-205283A | 100 ml 500 ml | $84.00 $129.00 | 3 | |
Limonene activates OR51L1 due to its terpene structure which is similar to natural odorants, binding to the receptor, causing a structural change and activating the G-protein coupled olfactory signaling pathway. | ||||||
4-Methoxybenzaldehyde | 123-11-5 | sc-238884 sc-238884A sc-238884B sc-238884C | 5 g 100 g 250 g 1 kg | $30.00 $42.00 $72.00 $124.00 | ||
Anisaldehyde activates OR51L1 by binding to the olfactory receptor's ligand-binding domain, inducing an activation of the receptor, and thereby initiating the G-protein coupled signaling processes. | ||||||
Vanillin | 121-33-5 | sc-251423 sc-251423A | 100 g 500 g | $44.00 $124.00 | 1 | |
Vanillin activates OR51L1 by binding to the odorant receptor and inducing a conformational change that activates the G-protein coupled receptor pathway involved in the olfactory signal transduction. | ||||||
2-Phenylethanol | 60-12-8 | sc-238198 | 250 ml | $69.00 | ||
Phenylethyl alcohol activates OR51L1 as it is a floral scent compound with a structure capable of binding to olfactory receptors, thereby causing an activation of the receptor and the associated signaling mechanism. | ||||||
Hexanal | 66-25-1 | sc-252885 | 2 ml | $27.00 | ||
Hexanal activates OR51L1 through binding to the olfactory receptor, its aldehyde group interacts with receptor sites, causing a conformational change and activation of the G-protein coupled olfactory signaling pathway. | ||||||
Geraniol | 106-24-1 | sc-235242 sc-235242A | 25 g 100 g | $45.00 $119.00 | ||
Geraniol activates OR51L1 by interacting with the receptor's ligand-binding site due to its structure as a monoterpenoid, leading to receptor activation and subsequent activation of the G-protein mediated signaling cascade. | ||||||
α-Ionone | 127-41-3 | sc-239157 | 100 g | $75.00 | ||
Alpha-ionone activates OR51L1 by mimicking the structure of natural odorants, binding to the receptor's active site, inducing a conformational change that leads to the activation of the receptor and its signaling pathways. | ||||||