OR51A7 Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin is an activator of adenylate cyclase, leading to increased cAMP levels. Elevated cAMP may desensitize GPCRs like OR51A7 by promoting receptor phosphorylation and subsequent internalization. | ||||||
Propranolol | 525-66-6 | sc-507425 | 100 mg | $180.00 | ||
Propranolol is a non-selective beta-adrenergic receptor antagonist that can decrease cAMP levels. This can reduce the functional activity of GPCRs like OR51A7 by limiting G protein signaling. | ||||||
Pertussis Toxin (islet-activating protein) | 70323-44-3 | sc-200837 | 50 µg | $442.00 | 3 | |
Pertussis toxin inhibits Gi/o protein signaling, which could decrease inhibitory feedback on adenylate cyclase, indirectly affecting OR51A7 function by altering GPCR signaling dynamics. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
PMA activates protein kinase C (PKC), which can phosphorylate GPCRs and modulate their activity. PKC-mediated phosphorylation could lead to OR51A7 desensitization or internalization. | ||||||
Bisindolylmaleimide I (GF 109203X) | 133052-90-1 | sc-24003A sc-24003 | 1 mg 5 mg | $103.00 $237.00 | 36 | |
GF 109203X is a potent PKC inhibitor. By inhibiting PKC, it can prevent the phosphorylation and subsequent desensitization of GPCRs, potentially decreasing OR51A7 signaling. | ||||||
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
Staurosporine is a broad-spectrum kinase inhibitor that could impede kinase-mediated phosphorylation processes of GPCRs, including OR51A7, thereby influencing its activity. | ||||||
Brefeldin A | 20350-15-6 | sc-200861C sc-200861 sc-200861A sc-200861B | 1 mg 5 mg 25 mg 100 mg | $30.00 $52.00 $122.00 $367.00 | 25 | |
Brefeldin A disrupts Golgi apparatus function, which could impair GPCR processing and trafficking to the membrane, potentially reducing OR51A7 surface expression and function. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $94.00 $349.00 | 114 | |
Thapsigargin is a SERCA pump inhibitor that leads to increased cytosolic calcium levels. Elevated intracellular calcium can modulate GPCR activity, potentially leading to decreased OR51A7 signaling. | ||||||
Clozapine | 5786-21-0 | sc-200402 sc-200402A | 50 mg 500 mg | $68.00 $357.00 | 11 | |
Clozapine is an antipsychotic known to interact with various GPCRs; it could allosterically influence OR51A7 activity by modulating the receptor microenvironment or signaling partners. | ||||||