OR4K5 Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Icilin | 36945-98-9 | sc-201557 sc-201557A | 10 mg 50 mg | $89.00 $252.00 | 9 | |
Agonist for transient receptor potential (TRP) channels, specifically TRPM8 and TRPA1, which are involved in thermosensation. Activation of these channels can modulate the olfactory signaling by competing with OR4K5-related pathways due to cross-talk between thermosensory and olfactory sensory neurons, leading to inhibition. | ||||||
Capsaicin | 404-86-4 | sc-3577 sc-3577C sc-3577D sc-3577A | 50 mg 250 mg 500 mg 1 g | $94.00 $173.00 $255.00 $423.00 | 26 | |
Activator of the TRPV1 channel, which is implicated in the sensation of heat. This activation may inhibit OR4K5 function by altering the sensory neuron environment, indirectly affecting olfactory receptor activity due to competition for intracellular signaling molecules and pathways. | ||||||
(±)-Menthol | 89-78-1 | sc-250299 sc-250299A | 100 g 250 g | $38.00 $67.00 | ||
Agonist for TRPM8 channels. Its action can indirectly inhibit OR4K5 by altering sensory neuron signaling through a competitive effect on the shared intracellular pathways that process sensory stimuli, leading to decreased OR4K5 activity. | ||||||
Ruthenium red | 11103-72-3 | sc-202328 sc-202328A | 500 mg 1 g | $184.00 $245.00 | 13 | |
Non-selective blocker of TRP channels, which can lead to a decrease in the activity of sensory neurons, indirectly inhibiting the olfactory signaling pathways that OR4K5 is involved in, due to the interplay between different sensory modalities and the shared downstream signaling components. | ||||||
Chloroform | 67-66-3 | sc-239527A sc-239527 | 1 L 4 L | $110.00 $200.00 | 1 | |
Can indirectly inhibit OR4K5 by altering the lipid environment of the olfactory receptor neurons, which may change the receptor's conformation or accessibility to its ligands, leading to reduced activity. | ||||||
Eugenol | 97-53-0 | sc-203043 sc-203043A sc-203043B | 1 g 100 g 500 g | $31.00 $61.00 $214.00 | 2 | |
Known to affect ion channels in sensory neurons. It may indirectly inhibit OR4K5 by modulating the activity of these channels, which are part of the signal transduction mechanisms in olfactory neurons, leading to the alteration of intracellular signaling cascades that are essential for OR4K5 function. | ||||||
Copper(II) sulfate | 7758-98-7 | sc-211133 sc-211133A sc-211133B | 100 g 500 g 1 kg | $45.00 $120.00 $185.00 | 3 | |
Known to interact with and inhibit various ion channels and membrane receptors. It may indirectly inhibit OR4K5 by binding to and altering the function of these ion channels in olfactory neurons, affecting the signal transduction processes that OR4K5 participates in. | ||||||
Pentyl acetate | 628-63-7 | sc-215691 | 250 ml | $65.00 | ||
Often used as an odorant in olfactory studies, it may saturate olfactory receptors and indirectly inhibit OR4K5 through competitive inhibition, as it could occupy OR4K5 binding sites, preventing the receptor from interacting with its specific ligands. | ||||||
Methyl Salicylate | 119-36-8 | sc-204802 sc-204802A | 250 ml 500 ml | $46.00 $69.00 | ||
A compound with odorant properties that may engage multiple olfactory receptors, potentially causing competitive inhibition of OR4K5 by occupying its ligand-binding sites or altering the receptor conformation, leading to inhibition of its signaling activity. | ||||||
Diethyl phthalate | 84-66-2 | sc-239738 sc-239738A | 25 ml 500 ml | $26.00 $32.00 | ||
Known to affect olfactory receptors and could indirectly inhibit OR4K5 activity by competitive binding or by altering the receptor's conformation, thereby diminishing its ability to signal upon ligand binding. | ||||||