OR4K17 Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Brefeldin A | 20350-15-6 | sc-200861C sc-200861 sc-200861A sc-200861B | 1 mg 5 mg 25 mg 100 mg | $31.00 $53.00 $124.00 $374.00 | 25 | |
This compound disrupts the protein transport from the endoplasmic reticulum to the Golgi apparatus. By hampering the vesicular transport mechanism, it indirectly affects the trafficking and proper localization of OR4K17 to the olfactory neuron membrane, decreasing its functional activity. | ||||||
Capsazepine | 138977-28-3 | sc-201098 sc-201098A | 5 mg 25 mg | $148.00 $459.00 | 11 | |
A vanilloid receptor antagonist that blocks the receptor-operated channel, selective for sensory neurons. It indirectly inhibits OR4K17 by modulating ion channels and neuronal excitability, which are essential for the signal transduction processes that OR4K17 is involved in. | ||||||
Cyclopiazonic Acid | 18172-33-3 | sc-201510 sc-201510A | 10 mg 50 mg | $176.00 $624.00 | 3 | |
An inhibitor of the sarcoplasmic/endoplasmic reticulum Ca2+-ATPase (SERCA), leading to a depletion of intracellular calcium stores. By altering calcium dynamics within olfactory neurons, it inadvertently impacts the function of OR4K17, whose activity is modulated by calcium levels. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
A tyrosine kinase inhibitor that can alter phosphorylation states of proteins, affecting multiple signaling pathways. It indirectly inhibits OR4K17 by disrupting the phosphorylation-dependent processes in olfactory transduction mechanisms where OR4K17 is involved. | ||||||
Phenylmethylsulfonyl Fluoride | 329-98-6 | sc-3597 sc-3597A | 1 g 100 g | $50.00 $697.00 | 92 | |
An irreversible inhibitor of serine proteases that can affect the proteolytic processing of signaling molecules. This action indirectly inhibits OR4K17 by potentially altering the processing and function of proteins that participate in OR4K17-mediated signal transduction. | ||||||
Quinine | 130-95-0 | sc-212616 sc-212616A sc-212616B sc-212616C sc-212616D | 1 g 5 g 10 g 25 g 50 g | $79.00 $104.00 $166.00 $354.00 $572.00 | 1 | |
A known inhibitor of voltage-gated K+ channels. By modulating the activity of these channels, it can affect neuronal excitability and indirectly inhibit the signal transduction pathways involving OR4K17. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $136.00 $446.00 | 114 | |
An inhibitor of the SERCA pump, causing a rise in cytosolic calcium levels. Due to the importance of calcium in olfactory signaling, this compound indirectly inhibits OR4K17 by dysregulating the calcium homeostasis that affects olfactory signal transduction. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $48.00 | ||
Acts as an allosteric modulator of various neurotransmitter receptors, including GPCRs. It can indirectly inhibit OR4K17 by causing structural changes in the receptor or neighboring proteins that affect OR4K17's ability to bind ligands or transduce signals. | ||||||