OR4D10 Activators
Chemical activators of the olfactory receptor OR4D10 can initiate a sequence of events leading to the detection of various scents. Benzaldehyde, a compound with an almond-like odor, can bind to OR4D10, causing a conformational shift in the receptor's structure. This shift enables the receptor to interact with and activate associated G-protein complexes within olfactory sensory neurons. Similarly, isoamyl acetate, known for its banana-like aroma, can also bind to this receptor, triggering a comparable activation process. The binding of these odorant molecules to OR4D10 is the first step in a cascade of intracellular reactions that culminate in the generation of a nerve impulse that the brain interprets as a distinct smell.
Eugenol, which possesses a clove-like scent, interacts with OR4D10 to produce a similar effect. Anethole, known for its licorice aroma, and citral, with its lemon scent, likewise engage with OR4D10, leading to the activation of the receptor's G-protein signaling pathways. Terpenes like limonene and linalool, which are responsible for citrus and floral fragrances respectively, also function as activators for OR4D10. These interactions result in the initiation of signal transduction mechanisms that translate chemical signals into the perception of smell. Other chemicals such as methyl salicylate, α-pinene, and β-caryophyllene demonstrate the versatility of OR4D10 in recognizing and responding to a wide variety of odorant molecules. Hexanal, with its grassy note, also binds to OR4D10, further exemplifying the diverse array of scents that this olfactory receptor can detect and translate into sensory information. Each of these chemicals, upon binding to OR4D10, contributes to the complex and nuanced sense of smell by activating the receptor and its downstream signaling pathways.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Isopentyl acetate | 123-92-2 | sc-250190 sc-250190A | 100 ml 500 ml | $107.00 $225.00 | ||
Isoamyl acetate is another odorant recognized by olfactory receptors. Its binding to OR4D10 would cause a conformational change, initiating a G-protein-coupled receptor cascade, resulting in the activation of OR4D10. | ||||||
Eugenol | 97-53-0 | sc-203043 sc-203043A sc-203043B | 1 g 100 g 500 g | $32.00 $62.00 $218.00 | 2 | |
Eugenol is a scent compound that can bind to and activate certain olfactory receptors. When bound to OR4D10, it triggers a G-protein signaling pathway, leading to the activation of downstream signaling events. | ||||||
Anethole | 104-46-1 | sc-481571A sc-481571 | 10 g 100 g | $576.00 $316.00 | ||
Anethole is a flavoring substance that can activate olfactory receptors. Its interaction with OR4D10 would lead to the activation of the receptor and its associated G-protein signaling pathway. | ||||||
Citral | 5392-40-5 | sc-252620 | 1 kg | $212.00 | ||
Citral, present in lemon and other citrus oils, can activate olfactory receptors. Binding to OR4D10 activates the receptor, which then activates the associated G-protein signaling pathway. | ||||||
Geraniol | 106-24-1 | sc-235242 sc-235242A | 25 g 100 g | $45.00 $119.00 | ||
Geraniol, a monoterpenoid and alcohol, is a natural fragrance that can activate olfactory receptors. OR4D10 activation occurs upon binding, initiating signal transduction in olfactory neurons. | ||||||
D-Limonene | 5989-27-5 | sc-205283 sc-205283A | 100 ml 500 ml | $84.00 $129.00 | 3 | |
Limonene, a citrus scent constituent, can activate olfactory receptors. Upon binding to OR4D10, it activates the receptor, leading to the activation of the G-protein signaling pathway. | ||||||
Linalool | 78-70-6 | sc-250250 sc-250250A sc-250250B | 5 g 100 g 500 g | $47.00 $72.00 $110.00 | ||
Linalool is a terpene alcohol found in many flowers and spice plants and can activate olfactory receptors. Interaction with OR4D10 leads to receptor activation and G-protein signaling. | ||||||
Methyl Salicylate | 119-36-8 | sc-204802 sc-204802A | 250 ml 500 ml | $47.00 $70.00 | ||
Methyl salicylate is an organic ester naturally occurring in various plants. Its binding activates OR4D10, which in turn activates the associated G-protein signaling pathway. | ||||||
α-Pinene | 80-56-8 | sc-233784 sc-233784A | 5 ml 250 ml | $52.00 $115.00 | 2 | |
α-Pinene is a natural organic compound found in pine and other plants. It activates olfactory receptors, and its binding to OR4D10 leads to activation of the G-protein signaling pathway. | ||||||
(−)-trans-Caryophyllene | 87-44-5 | sc-251281 sc-251281A sc-251281B sc-251281C | 1 ml 5 ml 25 ml 1 L | $81.00 $160.00 $446.00 $2918.00 | 1 | |
β-Caryophyllene is a natural bicyclic sesquiterpene that can activate certain olfactory receptors. Binding to OR4D10 activates the receptor and its associated signaling pathways. | ||||||