Date published: 2026-4-1

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OR10Z1 Inhibitors

Chemical inhibitors of Olfactory receptor 10Z1 employ various mechanisms to impede the receptor's function. Methyl Salicylate, Limonene, Vanillin, 1,8-Cineole, Citral, Isoeugenol, Geraniol, cis-3,7-Dimethyl-2,6-octadien-1-ol, Cinnamyl Alcohol, Anethole, Thymol, and Carvone are notable examples. These chemicals primarily engage in competitive inhibition, where they bind to the active sites of Olfactory receptor 10Z1, blocking the access of natural odorants. This binding is not merely superficial; it induces a conformational change in the receptor. For example, Methyl Salicylate and Limonene inhibit the receptor by occupying its ligand-binding domain, leading to structural alterations that reduce the receptor's ability to bind natural ligands. Similarly, 1,8-Cineole and Isoeugenol act by binding to specific sites on the receptor, causing changes in its structure that hinder its interaction with odorant molecules. Vanillin and Citral, like other inhibitors, mimic the structure of natural odorants, thereby competing for binding sites on Olfactory receptor 10Z1. This competitive binding is crucial in inhibiting the receptor's olfactory function. Geraniol and cis-3,7-Dimethyl-2,6-octadien-1-ol employ a similar strategy, preventing the natural odorants from binding to the receptor and thus inhibiting olfactory signaling. Cinnamyl Alcohol, Anethole, and Thymol also contribute to this inhibition by binding to the receptor's ligand-binding site or specific functional groups within its structure. This interaction results in a conformational change that diminishes the receptor's efficacy in detecting odorants. Carvone rounds out this group by also engaging in competitive inhibition, demonstrating the diverse yet specific ways these chemicals can inhibit Olfactory receptor 10Z1, each ensuring that the receptor's ability to conduct olfactory signaling is effectively reduced.

Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Methyl Salicylate

119-36-8sc-204802
sc-204802A
250 ml
500 ml
$47.00
$70.00
(1)

Methyl Salicylate inhibits Olfactory receptor 10Z1 by competitively binding to its active sites, preventing the binding of natural odorant molecules and thus inhibiting the receptor's olfactory signaling.

D-Limonene

5989-27-5sc-205283
sc-205283A
100 ml
500 ml
$84.00
$129.00
3
(1)

Limonene acts as an inhibitor of Olfactory receptor 10Z1 by binding to the receptor's ligand-binding domain, causing a conformational change that reduces the receptor's ability to bind to its natural ligands and inhibits its sensory function.

Vanillin

121-33-5sc-251423
sc-251423A
100 g
500 g
$44.00
$124.00
1
(1)

Vanillin inhibits Olfactory receptor 10Z1 through a mechanism of competitive inhibition, where it competes with natural odorants for binding sites on the receptor, reducing the receptor's ability to detect these odorants and inhibiting its olfactory function.

1,8-Cineole

470-82-6sc-485261
25 ml
$44.00
2
(0)

1,8-Cineole inhibits Olfactory receptor 10Z1 by binding to specific sites on the receptor, leading to an alteration in its structure. This structural modification hinders the receptor's ability to interact with odorant molecules, thereby inhibiting its sensory function.

Citral

5392-40-5sc-252620
1 kg
$212.00
(1)

Citral acts as an inhibitor of Olfactory receptor 10Z1 by competitively binding to the receptor's active sites, which interferes with the binding of natural odorants and consequently inhibits the receptor's function in olfactory perception.

Isoeugenol

97-54-1sc-250186
sc-250186A
5 g
100 g
$63.00
$53.00
(0)

Isoeugenol inhibits Olfactory receptor 10Z1 through a competitive inhibition mechanism, where it mimics the structure of natural odorants and binds to the receptor's active sites, thus preventing the natural ligands from binding and inhibiting the receptor's function.

Geraniol

106-24-1sc-235242
sc-235242A
25 g
100 g
$45.00
$119.00
(0)

Geraniol inhibits Olfactory receptor 10Z1 by binding to the receptor's ligand-binding site, leading to a conformational change that impairs the receptor's ability to bind to its natural ligands, thereby inhibiting its olfactory signaling.

cis-3,7-Dimethyl-2,6-octadien-1-ol

106-25-2sc-234382
5 ml
$51.00
(0)

cis-3,7-Dimethyl-2,6-octadien-1-ol inhibits Olfactory receptor 10Z1 by engaging in competitive inhibition, where it occupies the active sites of the receptor and prevents the binding of natural odorants, thus inhibiting the receptor's olfactory function.

trans-Anethole

4180-23-8sc-253727
1 ml
$28.00
1
(0)

Anethole acts as an inhibitor of Olfactory receptor 10Z1 by competitively binding to the receptor's active sites, which prevents the natural odorants from interacting with the receptor, thereby inhibiting its olfactory signaling.

Thymol

89-83-8sc-215984
sc-215984A
100 g
500 g
$97.00
$193.00
3
(0)

Thymol inhibits Olfactory receptor 10Z1 by binding to specific functional groups within the receptor's structure, leading to a conformational change that reduces the receptor's ability to interact with odorant molecules and inhibits its olfactory function.