OR10AG1 Activators
OR10AG1 engage the protein directly to initiate a cascade of biochemical events leading to its activation. Citronellol, a terpene, and eugenol, a phenylpropene, both interact with OR10AG1 through binding to the odorant-binding site of the receptor. This interaction results in a conformational change of OR10AG1, subsequently activating the G-protein coupled receptor (GPCR) signaling pathway. Similarly, geraniol, another terpene, and limonene, a cyclic monoterpene, bind to specific sites on OR10AG1, inducing structural changes that trigger G-protein signaling cascades, integral to the olfactory response. Menthol, with its cooling flavor profile, binds to the active site of OR10AG1, changing the receptor's structure and activating downstream pathways. α-Pinene takes a similar approach by docking into the receptor's binding pocket and initiating signal transduction processes specific to olfactory perception.
Benzaldehyde and isoamyl acetate function as activators of OR10AG1 by targeting the receptor's ligand-binding domain, leading to the activation of olfactory transduction pathways. Phenethyl alcohol interacts with OR10AG1, causing structural changes that result in the activation of the G-protein signaling cascade. β-Ionone and linalool also activate OR10AG1 upon binding, initiating signal transduction mechanisms crucial for sensory detection. Methyl salicylate engages OR10AG1 at its active site, prompting the receptor's activation and the subsequent olfactory signal transduction. Each of these chemicals, by virtue of their molecular interactions with OR10AG1, leads to the functional activation of the protein, playing a critical role in the conversion of chemical signals into the electrical signals that manifest as the sense of smell.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
(±)-beta-Citronellol | 106-22-9 | sc-294094 sc-294094A | 25 ml 500 ml | $32.00 $156.00 | ||
Citronellol is a terpene that can activate OR10AG1 by binding to the odorant-binding site, leading to a conformational change and subsequent activation of the G-protein coupled receptor signaling pathway, which OR10AG1 is part of. | ||||||
Eugenol | 97-53-0 | sc-203043 sc-203043A sc-203043B | 1 g 100 g 500 g | $32.00 $62.00 $218.00 | 2 | |
Eugenol binds to the olfactory receptors like OR10AG1, causing activation of the receptor and initiating the signal transduction cascade that converts chemical signals into electrical signals in the olfactory system. | ||||||
Geraniol | 106-24-1 | sc-235242 sc-235242A | 25 g 100 g | $45.00 $119.00 | ||
Geraniol interacts with OR10AG1 by fitting into its ligand-binding domain, thereby activating the receptor, which triggers a G-protein signaling cascade resulting in a cellular response to the odorant molecule. | ||||||
D-Limonene | 5989-27-5 | sc-205283 sc-205283A | 100 ml 500 ml | $84.00 $129.00 | 3 | |
Limonene activates OR10AG1 by binding to its designated site on the receptor, which in turn initiates a series of downstream reactions in the G-protein coupled receptor pathway leading to the perception of citrus odor. | ||||||
(±)-Menthol | 89-78-1 | sc-250299 sc-250299A | 100 g 250 g | $39.00 $68.00 | ||
Menthol can activate OR10AG1 by binding to the receptor's active site, which causes a change in the receptor's structure, leading to the activation of downstream signal transduction pathways. | ||||||
α-Pinene | 80-56-8 | sc-233784 sc-233784A | 5 ml 250 ml | $52.00 $115.00 | 2 | |
α-Pinene activates OR10AG1 by docking into its binding pocket, inducing a conformational change that triggers the signal transduction process inherent to the olfactory system. | ||||||
Isopentyl acetate | 123-92-2 | sc-250190 sc-250190A | 100 ml 500 ml | $107.00 $225.00 | ||
Isoamyl acetate activates OR10AG1 through its interaction with the binding site of the receptor, causing a conformational change that leads to the activation of the olfactory signaling pathway. | ||||||
2-Phenylethanol | 60-12-8 | sc-238198 | 250 ml | $69.00 | ||
2-Phenylethanol activates OR10AG1 by ligand-receptor interaction, causing structural changes that result in activation of the receptor and the associated G-protein signaling cascade. | ||||||
beta-Ionone | 14901-07-6 | sc-291976 | 25 ml | $83.00 | ||
β-Ionone activates OR10AG1 upon binding, which initiates signal transduction mechanisms specific to the olfactory system, where OR10AG1 functions as a sensory receptor. | ||||||
Linalool | 78-70-6 | sc-250250 sc-250250A sc-250250B | 5 g 100 g 500 g | $47.00 $72.00 $110.00 | ||
Linalool activates OR10AG1 by engaging with its ligand-binding domain, causing a structural change in the receptor that leads to activation of the linked G-protein signaling pathway. | ||||||