OR10A4 Activators
OR10A4 can initiate a complex molecular interaction by binding to this olfactory receptor, each chemical inducing a unique sensory experience. Benzaldehyde, for instance, engages with OR10A4, potentially causing a conformational alteration in the protein structure that results in its activation. This activation is the first step in the olfactory signal transduction pathway, leading to the perception of an almond-like odor. Similarly, eugenol, which is prevalent in essential oils, binds to OR10A4 and activates the receptor, triggering the G-protein-coupled signal cascade that culminates in a spicy, clove-like sensory response. Isoamyl acetate contributes to this array of scents by imparting a fruity banana odor when it interacts with OR10A4, thereby activating the receptor. Methyl salicylate, with its characteristic wintergreen scent, also binds to OR10A4 and initiates signal transduction mechanisms that result in the brain's perception of this particular scent.
Anethole, found in anise and fennel, directly influences OR10A4 by binding and causing protein conformational changes leading to the olfactory signaling pathway's activation. Citronellal, which offers a strong citrus scent, and geraniol, with its floral fragrance, both activate OR10A4 through direct binding, which induces structural changes in the receptor and initiates the olfactory signaling process. Isoeugenol and limonene, hailing from ylang-ylang and citrus sources respectively, serve as activators of OR10A4 by facilitating a conformational change in the protein upon binding, which in turn triggers the olfactory signal transduction pathway. Completing the sensory experience, vanilla-scented vanillin, as well as alpha-ionone and beta-ionone, which are reminiscent of violets, bind to OR10A4 and activate the receptor to initiate the cascade of signals that allows the perception of these distinct scents.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Eugenol | 97-53-0 | sc-203043 sc-203043A sc-203043B | 1 g 100 g 500 g | $31.00 $61.00 $214.00 | 2 | |
Eugenol, a compound commonly found in essential oils, has been shown to activate olfactory receptors. By binding to the ligand-binding site of OR10A4, eugenol can cause an activation of the receptor, triggering the G-protein coupled signal cascade that results in a sensory response. | ||||||
Isopentyl acetate | 123-92-2 | sc-250190 sc-250190A | 100 ml 500 ml | $105.00 $221.00 | ||
Isoamyl acetate is an ester that is known for its fruity banana odor and is a potential activator for OR10A4. By binding to specific sites on the protein, it can activate the receptor and initiate signal transduction pathways associated with smell. | ||||||
Methyl Salicylate | 119-36-8 | sc-204802 sc-204802A | 250 ml 500 ml | $46.00 $69.00 | ||
Methyl salicylate is a chemical with a wintergreen scent that can activate olfactory receptors such as OR10A4. Activation occurs through interaction with the olfactory receptor, leading to signal transduction mechanisms that communicate the perception of scent to the brain. | ||||||
Anethole | 104-46-1 | sc-481571A sc-481571 | 10 g 100 g | $565.00 $310.00 | ||
Anethole is a compound found in anise and fennel and is known to activate certain olfactory receptors by directly binding and causing receptor conformational changes, which in turn activate the OR10A4 protein function as part of the olfactory signaling pathway. | ||||||
(±)-Citronellal | 106-23-0 | sc-234400 | 100 ml | $51.00 | ||
Citronellal has a strong citrus scent and is known to activate olfactory receptors. It activates OR10A4 by binding to the receptor, changing its conformation, and initiating a signal transduction pathway that results in the perception of smell. | ||||||
Geraniol | 106-24-1 | sc-235242 sc-235242A | 25 g 100 g | $44.00 $117.00 | ||
Geraniol, a terpene with a floral scent, can activate olfactory receptors including OR10A4 through direct binding. This binding event likely causes a conformational change that activates the receptor, leading to olfactory signal transduction. | ||||||
Isoeugenol | 97-54-1 | sc-250186 sc-250186A | 5 g 100 g | $62.00 $52.00 | ||
Isoeugenol, found in ylang-ylang and other essential oils, is a known activator of olfactory receptors. It activates OR10A4 by binding directly to the protein, which induces a conformational shift that triggers signal transduction related to olfactory perception. | ||||||
D-Limonene | 5989-27-5 | sc-205283 sc-205283A | 100 ml 500 ml | $82.00 $126.00 | 3 | |
Limonene, a citrus-scented terpene, has been identified as an olfactory receptor activator. Interaction with OR10A4 would lead to protein activation by ligand-induced receptor conformational change, initiating a G-protein signaling cascade that communicates sensory information. | ||||||
Vanillin | 121-33-5 | sc-251423 sc-251423A | 100 g 500 g | $43.00 $122.00 | 1 | |
Vanillin, the primary component of vanilla bean extract, can serve as an activator for OR10A4 by directly binding to the receptor site, causing an activation of the olfactory signal transduction pathway. | ||||||
α-Ionone | 127-41-3 | sc-239157 | 100 g | $75.00 | ||
Alpha-ionone, with a scent reminiscent of violets, is capable of activating olfactory receptors. It binds to OR10A4 and activates the receptor, which leads to a signaling cascade that ultimately results in the perception of the scent. | ||||||