Olfr960, a gene that encodes a G protein-coupled receptor (GPCR), plays a vital role in the olfactory system of organisms. Its primary function is to serve as a molecular sensor for detecting and distinguishing a diverse range of odorants present in the environment. Through its activation, Olfr960 contributes significantly to an organism's sensory perception and interaction with its surroundings.
The activation of Olfr960 is a sophisticated process driven by odorant molecules. When specific odorants come into contact with Olfr960, they engage with the receptor's extracellular domain, initiating a sequence of events that lead to its activation. This activation involves a complex interplay of intracellular signaling pathways, including cyclic AMP (cAMP), phosphoinositide 3-kinase (PI3K), mitogen-activated protein kinase (MAPK), Wnt/β-catenin, calcium release, Janus kinase/signal transducers and activators of transcription (JAK/STAT), and inositol trisphosphate (IP3) signaling. Each of these pathways contributes to the functional activation of Olfr960, ultimately resulting in the generation of sensory signals that are transmitted to the brain for the perception and discrimination of various odors. In summary, Olfr960 is a crucial component of the olfactory system, enabling organisms to detect and differentiate a wide array of odorants. Its activation is a complex process orchestrated by the binding of specific odorants and the subsequent initiation of intracellular signaling pathways. This process enriches an organism's sensory experience, allowing it to interpret and respond to the myriad of scents in its environment.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Isopentyl acetate | 123-92-2 | sc-250190 sc-250190A | 100 ml 500 ml | $107.00 $225.00 | ||
Isopentyl acetate, a volatile ester, directly activates Olfr960 by binding to its extracellular domain. This interaction induces a conformational change that initiates olfactory signal transduction, ultimately leading to the functional activation of Olfr960. | ||||||
2-Heptanone | 110-43-0 | sc-238060 | 1 ml | $94.00 | ||
2-Heptanone activates Olfr960 as an odorant by binding to the receptor, inducing a conformational shift that initiates intracellular signaling pathways, resulting in the functional activation of Olfr960. | ||||||
Eugenol | 97-53-0 | sc-203043 sc-203043A sc-203043B | 1 g 100 g 500 g | $32.00 $62.00 $218.00 | 2 | |
Eugenol functions as an activator for Olfr960, serving as an odorant. When it interacts with the receptor, it induces a conformational change that initiates olfactory signaling pathways, ultimately leading to the activation of Olfr960 and the perception of its characteristic spicy scent. | ||||||
Acetophenone | 98-86-2 | sc-239189 | 5 g | $20.00 | ||
Acetophenone serves as an activator for Olfr960, functioning as an odorant. Upon binding to the receptor, it induces a conformational change that initiates olfactory signal transduction, resulting in the functional activation of Olfr960 and the perception of its almond-like odor. | ||||||
D-Limonene | 5989-27-5 | sc-205283 sc-205283A | 100 ml 500 ml | $84.00 $129.00 | 3 | |
Limonene, a natural terpene found in citrus fruits, activates Olfr960 as an odorant. It engages the receptor, causing a conformational shift that initiates olfactory signaling cascades, resulting in the functional activation of Olfr960 and the detection of citrus scents. | ||||||
Allyl isothiocyanate | 57-06-7 | sc-252361 sc-252361A sc-252361B | 5 g 100 g 500 g | $44.00 $67.00 $119.00 | 3 | |
Allyl isothiocyanate activates Olfr960 by binding to its extracellular domain as an odorant. This interaction triggers intracellular signaling cascades, leading to the activation of Olfr960 and the perception of pungent and spicy odors, such as those in mustard or horseradish. | ||||||
Octanal | 124-13-0 | sc-250612 sc-250612A | 25 ml 100 ml | $26.00 $34.00 | ||
Octanal activates Olfr960 as an odorant by binding to the receptor. This interaction triggers a conformational shift that initiates intracellular signaling cascades, leading to the functional activation of Olfr960 and the perception of its characteristic odor. | ||||||
Geraniol | 106-24-1 | sc-235242 sc-235242A | 25 g 100 g | $45.00 $119.00 | ||
Geraniol functions as an activator for Olfr960, serving as an odorant. When it interacts with the receptor, it induces a conformational change that initiates olfactory signaling pathways, ultimately leading to the activation of Olfr960 and the detection of its characteristic floral scent. | ||||||
Ethyl Acetate, HPLC | 141-78-6 | sc-360247 sc-360247A | 1 L 4 L | $122.00 $326.00 | ||
Ethyl acetate is a volatile compound that serves as an activator for Olfr960. It interacts with the receptor, inducing a conformational change that initiates olfactory signaling pathways, resulting in the functional activation of Olfr960. | ||||||
2-Propanol | 67-63-0 | sc-391000C sc-391000 sc-391000B sc-391000A | 1 ml 25 ml 100 ml 500 ml | $33.00 $53.00 $63.00 $89.00 | 1 | |
2-Propanol, also known as rubbing alcohol, activates Olfr960 by acting as a volatile odorant. It binds to the receptor's extracellular domain, triggering a conformational change that initiates olfactory signal transduction, leading to the activation of Olfr960. | ||||||