Olfr913 Activators
Olfr913 is an olfactory receptor protein, which plays a critical role in the detection and discrimination of odorant molecules. Olfactory receptors like Olfr913 are part of a large family of G-protein coupled receptors (GPCRs), which are key players in the transduction of olfactory signals from the external environment into the nervous system. The functional activation of these receptors is essential for the perception of odors, and this process begins with the binding of specific odorant molecules to the olfactory receptor sites. Upon binding, these receptors undergo a conformational change that triggers the activation of associated G-proteins. This activation leads to a cascade of intracellular signaling events, including the generation of secondary messengers like cyclic AMP (cAMP) and the increase of intracellular calcium levels. These events are crucial for the amplification of the olfactory signal and its transmission to the brain, where it is interpreted as a distinct smell.
The general mechanisms of activation of olfactory receptors, including Olfr913, involve the specific interaction between the odorant molecule and the receptor. The structural compatibility between the odorant and the receptor is key to this interaction. Each receptor has a unique binding site that accommodates specific chemical structures, allowing for the selective perception of various odors. Once an odorant molecule like ethyl acetate or benzaldehyde binds to Olfr913, it induces a conformational change in the receptor. This change is the primary trigger for the activation of downstream signaling pathways. The G-protein coupled pathways play a pivotal role in this process, where the activated G-protein initiates a series of intracellular reactions. These reactions lead to the production of secondary messengers, which further amplify the signal and result in the opening of ion channels, ultimately leading to a neural response. The specificity of this activation process allows for the distinct perception of odors, with each receptor responding to particular chemical stimuli. The diverse range of chemicals that can activate Olfr913 exemplifies the broad specificity that olfactory receptors can have, enabling the detection of a wide array of odorant molecules. This specificity and sensitivity are fundamental to the olfactory system's ability to discern a vast and complex array of scents in the environment.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Ethyl Acetate, HPLC | 141-78-6 | sc-360247 sc-360247A | 1 L 4 L | $122.00 $326.00 | ||
Ethyl acetate activates Olfr913 by interacting with its olfactory receptor sites. This small, volatile compound can easily diffuse through the nasal mucosa, reaching the olfactory receptors where it binds to Olfr913, leading to a conformational change in the protein structure, thus triggering signal transduction pathways that result in the activation of the receptor. | ||||||
Acetophenone | 98-86-2 | sc-239189 | 5 g | $20.00 | ||
Acetophenone activates Olfr913 through molecular binding at its specific olfactory receptor sites. This chemical's structural compatibility with Olfr913 enables it to bind effectively, altering the receptor's conformation. This binding triggers the activation of downstream G-protein coupled pathways, essential for the transduction of olfactory signals mediated by Olfr913. | ||||||
Isopentyl acetate | 123-92-2 | sc-250190 sc-250190A | 100 ml 500 ml | $107.00 $225.00 | ||
Isoamyl acetate, known for its banana-like scent, activates Olfr913 by binding to its specific olfactory binding sites. This interaction induces a conformational change in Olfr913, leading to the activation of olfactory signal transduction pathways. The binding of isoamyl acetate to Olfr913 effectively triggers the receptor's activation, resulting in the transmission of olfactory signals. | ||||||
Cinnamic Aldehyde | 104-55-2 | sc-294033 sc-294033A | 100 g 500 g | $104.00 $228.00 | ||
Cinnamic Aldehyde activates Olfr913 by binding to its olfactory receptor sites, triggering a conformational change. This interaction facilitates the activation of associated G-proteins, leading to the initiation of a series of intracellular signaling events. | ||||||
Anethole | 104-46-1 | sc-481571A sc-481571 | 10 g 100 g | $576.00 $316.00 | ||
Anethole activates Olfr913 through direct interaction with the receptor's binding sites. This binding induces a conformational change in the receptor, triggering the activation of G-protein coupled pathways. The subsequent intracellular signaling cascade, involving the rise of cyclic AMP, leads to the functional activation of Olfr913, essential for the olfactory perception associated with anethole. | ||||||
Vanillin | 121-33-5 | sc-251423 sc-251423A | 100 g 500 g | $44.00 $124.00 | 1 | |
Vanillin, a common flavor compound, activates Olfr913 by binding to its olfactory receptor sites, inducing a structural alteration. This interaction leads to the activation of G-protein coupled intracellular signaling pathways. The activation of these pathways, particularly the increase in intracellular calcium, plays a vital role in the functional activation of the olfactory receptor Olfr913. | ||||||
D-Limonene | 5989-27-5 | sc-205283 sc-205283A | 100 ml 500 ml | $84.00 $129.00 | 3 | |
Limonene activates Olfr913 by interacting with its specific olfactory receptor binding sites. This interaction induces a change in the receptor's structure, leading to the activation of G-protein coupled signal transduction pathways. The activation of these pathways, especially those involving cAMP, is essential for the functional activation of Olfr913, facilitating the perception of limonene's citrus scent. | ||||||
Eugenol | 97-53-0 | sc-203043 sc-203043A sc-203043B | 1 g 100 g 500 g | $32.00 $62.00 $218.00 | 2 | |
Eugenol activates Olfr913 by binding to its olfactory receptor sites, causing a conformational change in the receptor. This binding event triggers the activation of G-protein coupled pathways, leading to a cascade of intracellular signaling events. These events, particularly the increase in intracellular calcium levels, are crucial for the functional activation of the olfactory receptor Olfr913. | ||||||
Methyl Salicylate | 119-36-8 | sc-204802 sc-204802A | 250 ml 500 ml | $47.00 $70.00 | ||
Methyl salicylate activates Olfr913 by binding to its specific olfactory receptor sites. This interaction induces a structural change in the receptor, facilitating the activation of G-protein coupled signaling pathways. The activation of these pathways, including the elevation of cyclic AMP levels, plays a crucial role in the functional activation and signal transduction of the olfactory receptor Olfr913. | ||||||
Geraniol | 106-24-1 | sc-235242 sc-235242A | 25 g 100 g | $45.00 $119.00 | ||
Geraniol, a naturally occurring scent compound, activates Olfr913 through binding to its olfactory receptor sites. This interaction leads to a change in the receptor's conformation, triggering the activation of associated G-protein coupled signaling pathways. The activation of these pathways, particularly those involving the increase of cyclic AMP, is vital for the functional activation of Olfr913. | ||||||