Olfr904 is an olfactory receptor protein responsible for detecting specific odorants in our environment. Its activation is crucial for our sense of smell. Olfr904 directly recognizes and responds to odorant molecules by binding to its receptor site, initiating a conformational change. This change triggers olfactory signal transduction, leading to the functional activation of Olfr904. In addition to direct activation, Olfr904 can also be indirectly activated by chemicals like Cyclic AMP (cAMP) and Diacylglycerol (DAG). These compounds enhance olfactory receptor sensitivity by modulating intracellular pathways that increase responsiveness to odorants. Similarly, chemicals like Nitric Oxide (NO) and Phosphatidylinositol (PI) influence guanylyl cyclase (GC) and inositol trisphosphate (IP3), respectively, leading to increased intracellular messengers that enhance Olfr904's sensitivity to odorants.
In summary, Olfr904 is a vital component of our olfactory system, allowing us to perceive and distinguish various scents in our environment. Its activation is achieved through direct binding to odorants or indirectly by modulating intracellular pathways that enhance receptor sensitivity, ultimately leading to our ability to detect and recognize specific smells.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Isopentyl acetate | 123-92-2 | sc-250190 sc-250190A | 100 ml 500 ml | $107.00 $225.00 | ||
Isoamyl Acetate directly activates Olfr904 by binding to its receptor site, initiating a conformational change that triggers olfactory signal transduction, leading to the functional activation of Olfr904. | ||||||
2-Heptanone | 110-43-0 | sc-238060 | 1 ml | $94.00 | ||
2-Heptanone directly activates Olfr904 by binding to its receptor site, inducing a conformational change that initiates olfactory signal transduction, resulting in the functional activation of Olfr904. | ||||||
Ethyl butyrate | 105-54-4 | sc-214986 sc-214986A | 1 kg 4 kg | $100.00 $210.00 | ||
Ethyl Butyrate directly activates Olfr904 by binding to its receptor site, leading to a conformational change that initiates olfactory signal transduction, resulting in the functional activation of Olfr904. | ||||||
Methyl benzoate | 93-58-3 | sc-215338 sc-215338A | 25 g 500 g | $23.00 $33.00 | ||
Methyl Benzoate directly activates Olfr904 by binding to its receptor site, initiating a conformational change that triggers olfactory signal transduction, leading to the functional activation of Olfr904. | ||||||
beta-Ionone | 14901-07-6 | sc-291976 | 25 ml | $83.00 | ||
β-Ionone directly activates Olfr904 by binding to its receptor site, inducing a conformational change that initiates olfactory signal transduction, resulting in the functional activation of Olfr904. | ||||||
Adenosine 3′,5′-cyclic monophosphate | 60-92-4 | sc-217584 sc-217584A sc-217584B sc-217584C sc-217584D sc-217584E | 100 mg 250 mg 5 g 10 g 25 g 50 g | $116.00 $179.00 $265.00 $369.00 $629.00 $1150.00 | ||
Cyclic AMP (cAMP) indirectly activates Olfr904 by enhancing the sensitivity of olfactory receptors, including Olfr904, to odorant molecules. It modulates the olfactory signal transduction pathway, leading to increased responsiveness and the functional activation of Olfr904 in odor detection. | ||||||
1,2-Dioctanoyl-sn-glycerol | 60514-48-9 | sc-202397 sc-202397A | 10 mg 50 mg | $47.00 $254.00 | 2 | |
Diacylglycerol (DAG) indirectly activates Olfr904 by acting as a secondary messenger in the olfactory signal transduction pathway. It activates protein kinase C (PKC), which enhances the sensitivity of olfactory receptors, including Olfr904, to odorants. This modulation results in the functional activation of Olfr904 in the detection of specific scents. | ||||||
L-α-Phosphatidylinositol sodium salt | 383907-36-6 | sc-221821 | 10 mg | $408.00 | 1 | |
Phosphatidylinositol (PI) indirectly activates Olfr904 by modulating the olfactory signal transduction pathway. It generates inositol trisphosphate (IP3), leading to increased intracellular calcium levels and enhancing the responsiveness of olfactory receptors, including Olfr904, to odorants. This results in the functional activation of Olfr904 in odor detection. | ||||||
Isoniazid | 54-85-3 | sc-205722 sc-205722A sc-205722B | 5 g 50 g 100 g | $26.00 $101.00 $146.00 | ||
Isoniazid indirectly activates Olfr904 by stimulating the release of calcium ions from intracellular stores. This increased intracellular calcium enhances the responsiveness of olfactory receptors, including Olfr904, to odorants, facilitating their functional activation in odor detection. | ||||||