Olfr902 Activators
Olfr902 is an olfactory receptor protein responsible for detecting specific odorants in our environment. Its activation is crucial for our sense of smell. Olfr902 directly recognizes and responds to odorant molecules by binding to its receptor site, initiating a conformational change. This change triggers olfactory signal transduction, leading to the functional activation of Olfr902. In addition to direct activation, Olfr902 can also be indirectly activated by chemicals like Cyclic AMP (cAMP) and Diacylglycerol (DAG). These compounds enhance olfactory receptor sensitivity by modulating intracellular pathways that increase responsiveness to odorants. Similarly, chemicals like Nitric Oxide (NO) and Phosphatidylinositol (PI) influence guanylyl cyclase (GC) and inositol trisphosphate (IP3), respectively, leading to increased intracellular messengers that enhance Olfr902's sensitivity to odorants.
In summary, Olfr902 is a vital component of our olfactory system, allowing us to perceive and distinguish various scents in our environment. Its activation is achieved through direct binding to odorants or indirectly by modulating intracellular pathways that enhance receptor sensitivity, ultimately leading to our ability to detect and recognize specific smells.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Eugenol | 97-53-0 | sc-203043 sc-203043A sc-203043B | 1 g 100 g 500 g | $32.00 $62.00 $218.00 | 2 | |
Eugenol directly activates Olfr902 by binding to its receptor site, initiating a conformational change that triggers olfactory signal transduction, leading to the functional activation of Olfr902. | ||||||
Isopentyl butyrate | 106-27-4 | sc-269267 | 100 g | $67.00 | ||
Isoamyl Butyrate directly activates Olfr902 by binding to its receptor site, inducing a conformational change that initiates olfactory signal transduction, resulting in the functional activation of Olfr902. | ||||||
Methyl Salicylate | 119-36-8 | sc-204802 sc-204802A | 250 ml 500 ml | $47.00 $70.00 | ||
Methyl Salicylate directly activates Olfr902 by binding to its receptor site, leading to a conformational change that initiates olfactory signal transduction, resulting in the functional activation of Olfr902. | ||||||
Allyl isothiocyanate | 57-06-7 | sc-252361 sc-252361A sc-252361B | 5 g 100 g 500 g | $44.00 $67.00 $119.00 | 3 | |
Allyl Isothiocyanate directly activates Olfr902 by binding to its receptor site, inducing a conformational change that initiates olfactory signal transduction, resulting in the functional activation of Olfr902. | ||||||
(+)-Carvone | 2244-16-8 | sc-239480 sc-239480A | 5 ml 25 ml | $33.00 $84.00 | 2 | |
Carvone directly activates Olfr902 by binding to its receptor site, leading to a conformational change that initiates olfactory signal transduction, resulting in the functional activation of Olfr902. | ||||||
Adenosine 3′,5′-cyclic monophosphate | 60-92-4 | sc-217584 sc-217584A sc-217584B sc-217584C sc-217584D sc-217584E | 100 mg 250 mg 5 g 10 g 25 g 50 g | $116.00 $179.00 $265.00 $369.00 $629.00 $1150.00 | ||
Cyclic AMP (cAMP) indirectly activates Olfr902 by enhancing the sensitivity of olfactory receptors, including Olfr902, to odorant molecules. It modulates the olfactory signal transduction pathway, leading to increased responsiveness and the functional activation of Olfr902 in odor detection. | ||||||
1,2-Dioctanoyl-sn-glycerol | 60514-48-9 | sc-202397 sc-202397A | 10 mg 50 mg | $47.00 $254.00 | 2 | |
Diacylglycerol (DAG) indirectly activates Olfr902 by acting as a secondary messenger in the olfactory signal transduction pathway. It activates protein kinase C (PKC), which enhances the sensitivity of olfactory receptors, including Olfr902, to odorants. This modulation results in the functional activation of Olfr902 in the detection of specific scents. | ||||||
L-α-Phosphatidylinositol sodium salt | 383907-36-6 | sc-221821 | 10 mg | $408.00 | 1 | |
Phosphatidylinositol (PI) indirectly activates Olfr902 by modulating the olfactory signal transduction pathway. It generates inositol trisphosphate (IP3), leading to increased intracellular calcium levels and enhancing the responsiveness of olfactory receptors, including Olfr902, to odorants. This results in the functional activation of Olfr902 in odor detection. | ||||||
Isoniazid | 54-85-3 | sc-205722 sc-205722A sc-205722B | 5 g 50 g 100 g | $26.00 $101.00 $146.00 | ||
Isoniazid indirectly activates Olfr902 by stimulating the release of calcium ions from intracellular stores. This increased intracellular calcium enhances the responsiveness of olfactory receptors, including Olfr902, to odorants, facilitating their functional activation in odor detection. | ||||||