Olfr9 is an olfactory receptor protein responsible for detecting specific odorants in our environment. Its activation is essential for our sense of smell. Olfr9 directly recognizes and responds to odorant molecules by binding to its receptor site, which triggers a conformational change. This change initiates olfactory signal transduction, leading to the functional activation of Olfr9. In addition to direct activation, Olfr9 can also be indirectly activated by chemicals like Cyclic AMP (cAMP) and Forskolin. These compounds enhance olfactory receptor sensitivity by modulating intracellular pathways such as the cAMP-PKA pathway. This results in the amplification of Olfr9's response to odorants, facilitating its functional activation in odor detection.
In summary, Olfr9 is a crucial component of our olfactory system, enabling us to perceive and distinguish various scents in our environment. Its activation is achieved through direct binding to odorants or indirectly by modulating intracellular pathways that enhance receptor sensitivity, ultimately leading to our ability to detect and recognize specific smells.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Ethyl butyrate | 105-54-4 | sc-214986 sc-214986A | 1 kg 4 kg | $100.00 $210.00 | ||
Ethyl Butyrate directly activates Olfr9 by binding to its receptor site, leading to a conformational change that triggers olfactory signal transduction, ultimately resulting in the functional activation of Olfr9. | ||||||
Isopentyl acetate | 123-92-2 | sc-250190 sc-250190A | 100 ml 500 ml | $107.00 $225.00 | ||
Isoamyl Acetate directly activates Olfr9 by binding to its receptor site, initiating a conformational change that triggers olfactory signal transduction, leading to the functional activation of Olfr9. | ||||||
Pentyl acetate | 628-63-7 | sc-215691 | 250 ml | $66.00 | ||
Pentyl Acetate directly activates Olfr9 by binding to its receptor site, inducing a conformational change that triggers olfactory signal transduction, resulting in the functional activation of Olfr9. | ||||||
2-Heptanone | 110-43-0 | sc-238060 | 1 ml | $94.00 | ||
2-Heptanone directly activates Olfr9 by binding to its receptor site, initiating a conformational change that triggers olfactory signal transduction, leading to the functional activation of Olfr9. | ||||||
2-Nonanone | 821-55-6 | sc-238184 sc-238184A | 5 g 100 g | $47.00 $84.00 | ||
2-Nonanone directly activates Olfr9 by binding to its receptor site, inducing a conformational change that triggers olfactory signal transduction, resulting in the functional activation of Olfr9. | ||||||
Adenosine 3′,5′-cyclic monophosphate | 60-92-4 | sc-217584 sc-217584A sc-217584B sc-217584C sc-217584D sc-217584E | 100 mg 250 mg 5 g 10 g 25 g 50 g | $116.00 $179.00 $265.00 $369.00 $629.00 $1150.00 | ||
Cyclic AMP (cAMP) indirectly activates Olfr9 by increasing intracellular cAMP levels, which amplifies the sensitivity of olfactory receptors, including Olfr9, to odorant molecules. This leads to functional activation of Olfr9 in the detection of specific scents. | ||||||
Geraniol | 106-24-1 | sc-235242 sc-235242A | 25 g 100 g | $45.00 $119.00 | ||
Geraniol indirectly activates Olfr9 by up-regulating its expression through specific signaling pathways. This increases the synthesis of Olfr9 protein, leading to a higher number of active receptors on the cell membrane and functional enhancement of odorant sensitivity. | ||||||
(±)-Citronellal | 106-23-0 | sc-234400 | 100 ml | $51.00 | ||
Citronellal indirectly activates Olfr9 by modulating the olfactory signaling pathway, resulting in increased cAMP levels. This enhances the activity of olfactory receptors like Olfr9, facilitating their functional activation in odor detection. | ||||||
Isoproterenol Hydrochloride | 51-30-9 | sc-202188 sc-202188A | 100 mg 500 mg | $28.00 $38.00 | 5 | |
Isoproterenol indirectly activates Olfr9 by binding to beta-adrenergic receptors on olfactory neurons. This activation triggers the cAMP-PKA pathway, enhancing the sensitivity of olfactory receptors, including Olfr9, to odorants and promoting their functional activation in odor detection. | ||||||
3-Methyl-2-oxovaleric Acid | 1460-34-0 | sc-484817 | 1 g | $326.00 | ||
3-Methyl-2-oxovaleric acid indirectly activates Olfr9 by influencing the olfactory signal transduction pathway. It enhances the production of cAMP, leading to increased PKA activity, which promotes the functional activation of Olfr9 by amplifying the receptor's response to odorant molecules. | ||||||