Olfr877 Activators
Olfr877, a member of the olfactory receptor family, plays a pivotal role in the olfactory system, which is responsible for the perception of odors in organisms. This G protein-coupled receptor (GPCR) is predominantly expressed in olfactory sensory neurons and is intricately involved in the process of detecting and transducing odorant signals. The primary function of Olfr877 is to facilitate the recognition and discrimination of various odor molecules, contributing significantly to the sense of smell in living organisms. The activation of Olfr877 is a complex and highly specialized process. When odorant molecules bind to Olfr877's receptor site, a cascade of intracellular events is initiated. These events lead to the functional activation of Olfr877 and subsequent signal transduction within olfactory sensory neurons. The mechanisms involved in Olfr877 activation include the binding of odorant molecules to the receptor, which induces conformational changes in the receptor protein. These changes trigger downstream signaling pathways, such as the cAMP-PKA pathway, the MAPK/ERK pathway, and the JAK-STAT pathway, all of which have been associated with Olfr877 activation. Additionally, the modulation of intracellular calcium levels and G-protein signaling plays a crucial role in the activation process. These intricate mechanisms collectively enable Olfr877 to initiate the perception of specific odors, allowing organisms to respond to their surrounding environment through the sense of smell.
In summary, Olfr877 is a vital component of the olfactory system, responsible for detecting and transducing odorant signals into neural impulses. Its activation involves a series of complex molecular events, including the binding of odorant molecules, conformational changes in the receptor, and the initiation of various intracellular signaling pathways. These mechanisms collectively enable Olfr877 to fulfill its role in the olfactory system, contributing to the rich and diverse experience of odor perception in organisms.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Isopentyl acetate | 123-92-2 | sc-250190 sc-250190A | 100 ml 500 ml | $107.00 $225.00 | ||
Isoamyl acetate directly activates Olfr877 by binding to its receptor site, initiating an olfactory signal transduction cascade that leads to protein activation. | ||||||
Eugenol | 97-53-0 | sc-203043 sc-203043A sc-203043B | 1 g 100 g 500 g | $32.00 $62.00 $218.00 | 2 | |
Eugenol activates Olfr877 by interacting with its receptor, resulting in the initiation of an olfactory signal transduction cascade and functional activation of the protein. | ||||||
(±)-Citronellal | 106-23-0 | sc-234400 | 100 ml | $51.00 | ||
Citronellal, upon binding to Olfr877, activates the olfactory receptor and initiates a signal transduction pathway, leading to protein activation. | ||||||
Geraniol | 106-24-1 | sc-235242 sc-235242A | 25 g 100 g | $45.00 $119.00 | ||
Geraniol directly stimulates Olfr877 by binding to its receptor site and triggering an olfactory signal transduction cascade for protein activation. | ||||||
D-Limonene | 5989-27-5 | sc-205283 sc-205283A | 100 ml 500 ml | $84.00 $129.00 | 3 | |
Limonene activates Olfr877 by binding to its receptor and initiating an olfactory signaling pathway, resulting in the functional activation of the protein. | ||||||
Linalool | 78-70-6 | sc-250250 sc-250250A sc-250250B | 5 g 100 g 500 g | $47.00 $72.00 $110.00 | ||
Linalool activates Olfr877 through its interaction with the receptor, initiating an olfactory signal transduction cascade and functional activation of the protein. | ||||||
(−)-Carvone | 6485-40-1 | sc-293985 sc-293985A | 25 ml 500 ml | $51.00 $230.00 | 2 | |
Carvone directly activates Olfr877 by binding to its receptor site and initiating an olfactory signaling pathway that leads to protein activation. | ||||||
2-Heptanone | 110-43-0 | sc-238060 | 1 ml | $94.00 | ||
2-Heptanone stimulates Olfr877 through its interaction with the receptor, initiating an olfactory signal transduction cascade and protein activation. | ||||||
Octanal | 124-13-0 | sc-250612 sc-250612A | 25 ml 100 ml | $26.00 $34.00 | ||
Octanal activates Olfr877 by binding to its receptor and initiating an olfactory signaling pathway, leading to the functional activation of the protein. | ||||||
Hexanal | 66-25-1 | sc-252885 | 2 ml | $27.00 | ||
Hexanal directly activates Olfr877 by binding to its receptor site, initiating an olfactory signal transduction cascade that leads to protein activation. | ||||||