Date published: 2025-10-15

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(−)-Carvone (CAS 6485-40-1)

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Alternate Names:
(R)-5-Isopropenyl-2-methyl-2-cyclohexenone, Carvol
CAS Number:
6485-40-1
Purity:
98%
Molecular Weight:
150.22
Molecular Formula:
C10H14O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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(−)-Carvone is a terpenoid that functions as a chiral agent and fragrance. (−)-Carvone distinct spearmint-like aroma. In development, (−)-Carvone is utilized for its ability to interact with olfactory receptors, eliciting a specific sensory response. At the molecular level, (−)-Carvone is believed to bind to and activate certain odorant receptors in the nasal epithelium, leading to the perception of its characteristic scent. This mechanism of action allows for the investigation of olfactory perception and the development of sensory-based products. (−)-Carvone′s involves its interaction with specific receptors to produce a discernible olfactory response, contributing to the understanding of sensory perception and the development of sensory-based products.


(−)-Carvone (CAS 6485-40-1) References

  1. Enantioselective penetration enhancing effect of carvone on the in vitro transdermal permeation of nicorandil.  |  Krishnaiah, YS. and Nada, A. 2012. Pharm Dev Technol. 17: 574-82. PMID: 21428701
  2. (-)-Carvone: antispasmodic effect and mode of action.  |  Souza, FV., et al. 2013. Fitoterapia. 85: 20-4. PMID: 23103297
  3. Spontaneous L-glutamate release enhancement in rat substantia gelatinosa neurons by (-)-carvone and (+)-carvone which activate different types of TRP channel.  |  Kang, Q., et al. 2015. Biochem Biophys Res Commun. 459: 498-503. PMID: 25747716
  4. Antimanic-like effects of (R)-(-)-carvone and (S)-(+)-carvone in mice.  |  Nogoceke, FP., et al. 2016. Neurosci Lett. 619: 43-8. PMID: 26970377
  5. Biotransformation of (+)-Carvone and (-)-Carvone by the Common Cutworm Spodoptera litura Larvae.  |  Marumoto, S., et al. 2018. J Oleo Sci. 67: 1253-1257. PMID: 30210079
  6. R-(-)-carvone Attenuated Doxorubicin Induced Cardiotoxicity In Vivo and Potentiated Its Anticancer Toxicity In Vitro.  |  Abbas, MM., et al. 2020. Balkan Med J. 37: 98-103. PMID: 31893584
  7. Novel (‒)-carvone derivatives as potential anticonvulsant and analgesic agents.  |  Nesterkina, M., et al. 2021. Nat Prod Res. 35: 4978-4987. PMID: 32336164
  8. Carvone Enantiomers Differentially Modulate IgE-Mediated Airway Inflammation in Mice.  |  Ribeiro-Filho, J., et al. 2020. Int J Mol Sci. 21: PMID: 33287119
  9. Hypolipidaemic and Insulin Secretagogue Activities of (R)-(-)-Carvone.  |  Abbas, MA., et al. 2020. Malays J Med Sci. 27: 39-52. PMID: 33447133
  10. Newly synthesized (R)-carvone-derived 1,2,3-triazoles: structural, mechanistic, cytotoxic and molecular docking studies.  |  Hachim, ME., et al. 2022. J Biomol Struct Dyn. 40: 7205-7217. PMID: 33719863
  11. Increased carvone production in Escherichia coli by balancing limonene conversion enzyme expression via targeted quantification concatamer proteome analysis.  |  Yoshida, E., et al. 2021. Sci Rep. 11: 22126. PMID: 34764337
  12. (-)-Carvone Modulates Intracellular Calcium Signaling with Antiarrhythmic Action in Rat Hearts.  |  Silva, GBAD., et al. 2022. Arq Bras Cardiol. 119: 294-304. PMID: 35946691
  13. (R)-Carvone is a potential soil fumigant against Meloidogyne incognita whose likely enzymatic target in the nematode is acetylcholinesterase.  |  Pacule, HB., et al. 2022. Exp Parasitol. 241: 108359. PMID: 35998723
  14. In vitro anthelmintic activity of an R-carvone nanoemulsions towards multiresistant Haemonchus contortus.  |  Aguiar, AARM., et al. 2022. Parasitology. 149: 1631-1641. PMID: 36052509
  15. Functional Study on Cytochrome P450 in Response to L(-)-Carvone Stress in Bursaphelenchus xylophilus.  |  Chen, J., et al. 2022. Genes (Basel). 13: PMID: 36360193

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

(−)-Carvone, 25 ml

sc-293985
25 ml
$50.00

(−)-Carvone, 500 ml

sc-293985A
500 ml
$225.00