Olfr862 is an olfactory receptor that is part of the G protein-coupled receptor (GPCR) superfamily. The activation of this receptor is highly specific, relying on the interaction between the receptor and odorant molecules, leading to the translation of chemical signals into electrical signals that the brain interprets as distinct odors. The activation mechanism of Olfr862 is characterized by a lock-and-key model, where each chemical's unique molecular structure allows it to fit into the active site of the receptor. This interaction induces a conformational change in Olfr862, activating an associated G protein. The activated G protein then initiates a cascade of intracellular signaling events, typically involving the production of cyclic AMP (cAMP) and the activation of protein kinase A (PKA). This sequence of events results in the generation of nerve impulses, which are transmitted to the brain and interpreted as specific smells.
The variety of chemical structures that can activate Olfr862 demonstrates the receptor's ability to detect a broad range of odorant molecules. This underscores the complexity of the olfactory system and its capacity for discerning a vast array of odors. The direct activation of Olfr862 by these chemicals highlights the significance of molecular structure in the olfactory detection process and provides insights into the molecular underpinnings of olfaction.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Pentyl acetate | 628-63-7 | sc-215691 | 250 ml | $66.00 | ||
Pentyl acetate activates Olfr862 through direct interaction with the receptor's binding site, leading to a conformational change and the initiation of olfactory signaling. | ||||||
Cinnamic Aldehyde | 104-55-2 | sc-294033 sc-294033A | 100 g 500 g | $104.00 $228.00 | ||
Cinnamic Aldehyde activates Olfr862 by directly interacting with the receptor, causing a conformational change that leads to the activation of the olfactory signal transduction cascade. | ||||||
Ethyl butyrate | 105-54-4 | sc-214986 sc-214986A | 1 kg 4 kg | $100.00 $210.00 | ||
Ethyl butyrate, an ester with a fruity odor, activates Olfr862 by direct interaction with its specific binding site, initiating a unique olfactory signaling process. | ||||||
Hexanal | 66-25-1 | sc-252885 | 2 ml | $27.00 | ||
Hexanal, a saturated aliphatic aldehyde, activates Olfr862 by fitting into its binding pocket, leading to a change in receptor conformation and triggering the olfactory signaling pathway. | ||||||
D-Limonene | 5989-27-5 | sc-205283 sc-205283A | 100 ml 500 ml | $84.00 $129.00 | 3 | |
Limonene, a naturally occurring terpene, activates Olfr862 by directly binding to the receptor, causing a structural change and initiating olfactory signaling. | ||||||
Methyl Salicylate | 119-36-8 | sc-204802 sc-204802A | 250 ml 500 ml | $47.00 $70.00 | ||
Methyl salicylate activates Olfr862 through direct interaction with the receptor, leading to a conformational change that triggers the olfactory signaling cascade. | ||||||
Octanal | 124-13-0 | sc-250612 sc-250612A | 25 ml 100 ml | $26.00 $34.00 | ||
Octanal, an aliphatic aldehyde, activates Olfr862 by binding to its ligand-binding domain, leading to a structural change and initiating the olfactory signal transduction. | ||||||
2-Phenylethanol | 60-12-8 | sc-238198 | 250 ml | $69.00 | ||
2-Phenylethanol, with a floral scent, activates Olfr862 through direct interaction with the receptor, causing a structural change and initiating the olfactory signaling process. | ||||||
Propyl acetate | 109-60-4 | sc-250792 | 500 ml | $20.00 | ||
Propyl acetate activates Olfr862 by binding to the receptor's active site, leading to a conformational change and triggering olfactory signal transduction. | ||||||
Vanillin | 121-33-5 | sc-251423 sc-251423A | 100 g 500 g | $44.00 $124.00 | 1 | |
Vanillin, a phenolic aldehyde, activates Olfr862 by fitting into its binding site, triggering a conformational change that leads to olfactory signal transduction. | ||||||