Olfr742 Activators
Olfr742 is a member of the olfactory receptor family, which plays a pivotal role in the olfactory system. These receptors are specialized G-protein coupled receptors (GPCRs), designed to detect and respond to a diverse array of odorant molecules. The specific activation of Olfr742, as with other olfactory receptors, is crucial for the discrimination and perception of distinct odors. The olfactory system's ability to identify a wide range of scents is largely attributed to the unique selectivity and specificity of these receptors. Olfr742, in particular, is tuned to recognize certain chemical compounds, allowing for the detection of specific odors and contributing to the complex olfactory landscape.
The mechanism of activation for Olfr742 begins with the binding of an odorant molecule, such as those listed in the table. This binding event is highly selective, as each receptor possesses a unique structure that determines its interaction with specific molecular configurations. Upon odorant binding, Olfr742 undergoes a conformational change, a critical step in the receptor's activation. This structural alteration leads to the activation of an associated G-protein, initiating a cascade of intracellular events. These events typically involve the production of second messengers such as cyclic AMP (cAMP) or inositol triphosphate (IP3). These messengers amplify the initial signal and result in a series of cellular responses, culminating in the perception of an odor. The specificity of Olfr742's response to the binding of particular odorant molecules is essential for the accurate identification and discrimination of various scents. The chemicals identified as potential activators of Olfr742, including amyl acetate, benzyl acetate, and linalool, represent a wide range of scents from fruity to floral to minty. Each chemical's ability to specifically bind and activate Olfr742 demonstrates the receptor's role in detecting different scents. This capability reflects the intricate design of the olfactory system, where slight variations in molecular structure can activate different receptors, contributing to our nuanced perception of smells. The function of Olfr742 in detecting and responding to these odorant molecules highlights the complexity and precision of olfactory perception, where the detection and recognition of a myriad of scents are facilitated by the specific interactions between odorant molecules and olfactory receptors.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Pentyl acetate | 628-63-7 | sc-215691 | 250 ml | $66.00 | ||
Pentyl acetate, known for its banana-like odor, can activate Olfr742 by directly binding to the receptor. This ester induces a conformational change in Olfr742, leading to the activation of the G-protein and subsequent intracellular signaling pathways critical for olfactory perception of banana-like scents. | ||||||
Benzyl acetate | 140-11-4 | sc-252427 | 100 g | $30.00 | 1 | |
Benzyl acetate, with a jasmine-like aroma, can activate Olfr742. It binds to the receptor, causing a conformational change that activates the G-protein, which then initiates signaling pathways responsible for the perception of jasmine-like aromas. | ||||||
Ethyl butyrate | 105-54-4 | sc-214986 sc-214986A | 1 kg 4 kg | $100.00 $210.00 | ||
Ethyl butyrate, a compound with a fruity odor, can activate Olfr742 through direct interaction. Upon binding, it induces a conformational change in the receptor, leading to the activation of G-protein mediated signaling cascades important for the sensory perception of fruity scents. | ||||||
Geraniol | 106-24-1 | sc-235242 sc-235242A | 25 g 100 g | $45.00 $119.00 | ||
Geraniol, a monoterpenoid and alcohol, can activate Olfr742. By binding to the receptor, geraniol triggers a conformational change, activating downstream G-protein mediated signaling pathways and participating in the olfactory perception process. | ||||||
Linalool | 78-70-6 | sc-250250 sc-250250A sc-250250B | 5 g 100 g 500 g | $47.00 $72.00 $110.00 | ||
Linalool, found in many flowers and spice plants, can activate Olfr742. Its interaction with olfactory receptors involves binding to the receptor, inducing a change that activates the G-protein, thus triggering signaling pathways responsible for olfactory perception. | ||||||
Methyl Salicylate | 119-36-8 | sc-204802 sc-204802A | 250 ml 500 ml | $47.00 $70.00 | ||
Methyl salicylate, or wintergreen oil, can activate Olfr742. This ester, with its minty scent, binds and activates olfactory receptors, leading to G-protein activation and subsequent signaling required for the perception of minty aromas. | ||||||
D-Limonene | 5989-27-5 | sc-205283 sc-205283A | 100 ml 500 ml | $84.00 $129.00 | 3 | |
D-Limonene, a citrus-scented terpene, can activate Olfr742 through direct interaction. As a component of citrus fruit odors, limonene binds to and activates olfactory receptors like Olfr742, triggering G-protein signaling pathways essential for the perception of citrus aromas. | ||||||
Hexanal | 66-25-1 | sc-252885 | 2 ml | $27.00 | ||
Hexanal, with a grassy odor, can activate Olfr742 through direct binding. As an aldehyde, it interacts with olfactory receptors by binding to them, leading to the activation of the G-protein coupled receptor pathway, a key mechanism in the detection of different odors. | ||||||
Citral | 5392-40-5 | sc-252620 | 1 kg | $212.00 | ||
Citral, known for its lemon scent, can activate Olfr742 by directly interacting with the receptor. This interaction leads to the activation of G-protein signaling pathways, which are crucial for the transduction of olfactory signals and perception of lemon-like odors. | ||||||
α-Pinene | 80-56-8 | sc-233784 sc-233784A | 5 ml 250 ml | $52.00 $115.00 | 2 | |
α-Pinene, a major component of pine resin, can activate Olfr742 by binding to it. This interaction induces a conformational change in the receptor, which in turn activates the G-protein, leading to the initiation of signaling pathways essential for the detection of pine-like scents. | ||||||