Olfr665 Inhibitors
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Items 1 to 10 of 19 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Eugenol | 97-53-0 | sc-203043 sc-203043A sc-203043B | 1 g 100 g 500 g | $31.00 $61.00 $214.00 | 2 | |
Eugenol activates Olfr665 by binding to its ligand-binding domain, inducing a conformational change, and triggering the GPCR signaling pathway for olfactory signal transduction. | ||||||
Lidocaine | 137-58-6 | sc-204056 sc-204056A | 50 mg 1 g | $50.00 $128.00 | ||
Lidocaine, a sodium channel blocker, indirectly inhibits Olfr665 by interfering with neuronal excitability. It disrupts action potentials in olfactory neurons, affecting the transmission of odorant signals and subsequently impairing the perception of smell. | ||||||
Vanillin | 121-33-5 | sc-251423 sc-251423A | 100 g 500 g | $43.00 $122.00 | 1 | |
Vanillin activates Olfr665 through direct interaction with the ligand-binding site, causing a structural change that leads to GPCR-mediated signal transduction related to olfaction. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $47.00 | ||
Zinc sulfate serves as a potential indirect inhibitor by modulating olfactory receptor expression. It influences the zinc-dependent regulation of olfactory receptor genes, including Olfr665, altering their transcription and impacting the overall olfactory response. | ||||||
Isopentyl acetate | 123-92-2 | sc-250190 sc-250190A | 100 ml 500 ml | $105.00 $221.00 | ||
Isopentyl acetate activates Olfr665 by binding to the receptor, mimicking natural ligands, and initiating the GPCR cascade for olfactory signal propagation. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin acts as a direct inhibitor by stimulating adenylate cyclase and increasing intracellular cAMP levels. This elevation in cAMP negatively regulates Olfr665-mediated signaling, leading to reduced responsiveness to odorant molecules and impaired smell perception. | ||||||
Budesonide | 51333-22-3 | sc-202980 sc-202980A sc-202980B sc-202980C | 50 mg 100 mg 200 mg 500 mg | $77.00 $88.00 $151.00 $343.00 | 3 | |
Budesonide, a glucocorticoid, indirectly inhibits Olfr665 through anti-inflammatory effects. It modulates the immune response in the nasal mucosa, influencing olfactory receptor function by reducing inflammation and maintaining normal olfactory signal transduction. | ||||||
D-Limonene | 5989-27-5 | sc-205283 sc-205283A | 100 ml 500 ml | $82.00 $126.00 | 3 | |
D-Limonene activates Olfr665 by binding to its ligand-binding domain, leading to a structural change in the receptor and activation of the GPCR pathway for olfactory perception. | ||||||
Methyl Salicylate | 119-36-8 | sc-204802 sc-204802A | 250 ml 500 ml | $46.00 $69.00 | ||
Methyl salicylate activates Olfr665 by interacting with the ligand-binding domain, causing a conformational change and initiating the GPCR pathway for olfactory signal transduction. | ||||||
Geraniol | 106-24-1 | sc-235242 sc-235242A | 25 g 100 g | $44.00 $117.00 | ||
Geraniol activates Olfr665 by binding to specific receptor sites, leading to a conformational change and the activation of G protein-mediated signal transduction for smell perception. | ||||||