Olfr63, a member of the olfactory receptor gene family, plays a pivotal role in the mammalian olfactory system, which is responsible for detecting and discriminating a wide range of odorant molecules. Positioned within the olfactory epithelium, Olfr63 functions as a molecular sensor, initiating a cascade of events upon activation that leads to the perception of distinct odors.
The activation of Olfr63 involves a highly specialized process triggered by the binding of specific odorant chemicals to the receptor's unique binding site. This binding interaction results in a conformational change in the receptor protein, leading to the activation of intracellular signaling pathways. These pathways include the activation of adenylate cyclase, which increases the production of cyclic adenosine monophosphate (cAMP). Elevated levels of cAMP, in turn, activate protein kinase A (PKA) and lead to the opening of ion channels, ultimately resulting in a change in membrane potential and the generation of action potentials in olfactory sensory neurons. These action potentials transmit olfactory information to the brain, where it is processed and interpreted, allowing us to perceive and identify various odors. In summary, Olfr63 is a crucial component of the olfactory system, facilitating the detection and discrimination of odorant molecules. Its activation process involves intricate molecular interactions and specific signaling pathways that enable the transmission of olfactory information to the central nervous system, contributing to our ability to perceive and respond to the diverse array of scents in our environment.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Cinnamic Aldehyde | 104-55-2 | sc-294033 sc-294033A | 100 g 500 g | $104.00 $228.00 | ||
Cinnamaldehyde specifically activates Olfr63 by binding to its receptor, promoting conformational changes, and initiating downstream signaling cascades, leading to functional activation. | ||||||
2-Heptanone | 110-43-0 | sc-238060 | 1 ml | $94.00 | ||
2-Heptanone directly activates Olfr63 by binding to the receptor and triggering intracellular signaling pathways, resulting in the functional activation of the protein. | ||||||
Isopentyl acetate | 123-92-2 | sc-250190 sc-250190A | 100 ml 500 ml | $107.00 $225.00 | ||
Isoamyl acetate serves as a specific activator of Olfr63, binding to the receptor and initiating downstream signaling events, ultimately resulting in the functional activation of the protein. | ||||||
Ethyl Acetate, HPLC | 141-78-6 | sc-360247 sc-360247A | 1 L 4 L | $122.00 $326.00 | ||
Ethyl acetate directly activates Olfr63 by binding to the receptor and initiating intracellular signaling pathways, leading to the functional activation of the protein. | ||||||
Ethyl butyrate | 105-54-4 | sc-214986 sc-214986A | 1 kg 4 kg | $100.00 $210.00 | ||
Ethyl butyrate specifically activates Olfr63 by binding to its receptor, promoting conformational changes, and initiating downstream signaling cascades, resulting in functional activation. | ||||||
Methyl Salicylate | 119-36-8 | sc-204802 sc-204802A | 250 ml 500 ml | $47.00 $70.00 | ||
Methyl salicylate directly activates Olfr63 by binding to the receptor and triggering intracellular signaling pathways, resulting in the functional activation of the protein. | ||||||
Acetophenone | 98-86-2 | sc-239189 | 5 g | $20.00 | ||
Acetophenone serves as a specific activator of Olfr63, binding to the receptor and initiating downstream signaling events, ultimately resulting in the functional activation of the protein. | ||||||
Pentyl acetate | 628-63-7 | sc-215691 | 250 ml | $66.00 | ||
Pentyl acetate directly activates Olfr63 by binding to the receptor and initiating intracellular signaling pathways, resulting in the functional activation of the protein. | ||||||
Isovaleraldehyde | 590-86-3 | sc-250204 sc-250204A | 25 ml 100 ml | $20.00 $39.00 | ||
Isovaleraldehyde specifically activates Olfr63, binding to its receptor and promoting conformational changes, initiating downstream signaling cascades, resulting in functional activation. | ||||||