Olfr608 Activators
Olfr608, part of the olfactory receptor family, plays a pivotal role in the detection and discrimination of odorous molecules. Functioning as a G-protein coupled receptor (GPCR), Olfr608's activation is contingent on the binding of specific ligands, which induce a series of intracellular events leading to odor perception. The activation process of Olfr608, like other olfactory receptors, necessitates the interaction with distinct chemical compounds that fit precisely into its binding site. This precise interaction leads to a structural alteration in the receptor, which is crucial for its activation. Subsequently, the activated state of Olfr608 enables the interaction with G-proteins, facilitating their dissociation and activation of downstream signaling pathways. These pathways often involve the production of secondary messengers such as cyclic AMP (cAMP), which further amplify the signal within the sensory neurons.
The mechanism of activation for Olfr608 follows the general GPCR activation model. When an agonist, such as the chemicals listed, binds to Olfr608, it transitions from an inactive to an active conformation. This structural transformation allows for interaction with G-proteins, triggering their activation. The activated G-proteins then dissociate into their alpha and beta-gamma subunits, interacting with other intracellular proteins and enzymes. This cascade of interactions leads to the generation of a nerve impulse that is transmitted to the brain, where it is interpreted as a specific odor. The specificity of Olfr608's interaction with its ligands highlights the complexity of the olfactory system, capable of discerning a vast array of odorous molecules. The direct activation of Olfr608 by specific chemicals underscores the precision and intricacy of olfactory perception at the molecular level, illustrating the sophisticated nature of sensory processing in the realm of smell.
SEE ALSO...
Items 1 to 10 of 11 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Methyl benzoate | 93-58-3 | sc-215338 sc-215338A | 25 g 500 g | $23.00 $32.00 | ||
Methyl Benzoate activates Olfr608 by binding directly to its receptor site, inducing a conformational change that initiates signal transduction, thereby activating downstream signaling pathways associated with Olfr608 function. | ||||||
Ethyl Acetate, HPLC | 141-78-6 | sc-360247 sc-360247A | 1 L 4 L | $120.00 $320.00 | ||
Ethyl Acetate interacts with Olfr608, leading to its activation through direct interaction. This interaction triggers the receptor's intrinsic activity, resulting in the activation of specific cellular signaling cascades. | ||||||
3-Methyl-1-butanol | 123-51-3 | sc-231818 sc-231818A | 500 ml 1 L | $70.00 $93.00 | ||
3-Methyl-1-butanol binds to Olfr608, promoting its active conformation. This binding event functionally activates Olfr608, initiating intracellular signaling processes characteristic of its activated state. | ||||||
2-Phenylethanol | 60-12-8 | sc-238198 | 250 ml | $68.00 | ||
2-Phenylethanol activates Olfr608 by directly interacting with its ligand-binding domain. This interaction induces a structural change in Olfr608, triggering its activation and subsequent signaling events. | ||||||
Cinnamic Aldehyde | 104-55-2 | sc-294033 sc-294033A | 100 g 500 g | $102.00 $224.00 | ||
Cinnamic Aldehyde facilitates the activation of Olfr608 by directly binding to it, promoting the receptor's active state and initiating downstream signaling pathways associated with Olfr608 activation. | ||||||
Vanillin | 121-33-5 | sc-251423 sc-251423A | 100 g 500 g | $43.00 $122.00 | 1 | |
Vanillin directly interacts with Olfr608, leading to its activation. This interaction prompts a conformational change in Olfr608, activating the receptor and subsequent signal transduction pathways. | ||||||
Ethyl butyrate | 105-54-4 | sc-214986 sc-214986A | 1 kg 4 kg | $100.00 $210.00 | ||
Ethyl Butyrate binds to Olfr608, inducing its activation by stabilizing the receptor in its active conformation, facilitating the subsequent activation of Olfr608-dependent signaling pathways. | ||||||
Geraniol | 106-24-1 | sc-235242 sc-235242A | 25 g 100 g | $44.00 $117.00 | ||
Geraniol directly activates Olfr608 by binding to its ligand-binding site, triggering a conformational change that leads to the activation of the receptor and its associated signaling pathways. | ||||||
Linalool | 78-70-6 | sc-250250 sc-250250A sc-250250B | 5 g 100 g 500 g | $46.00 $71.00 $108.00 | ||
Linalool activates Olfr608 through direct binding, inducing a conformational shift in the receptor that promotes its active state and initiates downstream signaling processes characteristic of Olfr608 activation. | ||||||
D-Limonene | 5989-27-5 | sc-205283 sc-205283A | 100 ml 500 ml | $82.00 $126.00 | 3 | |
Limonene interacts with Olfr608, activating the receptor by inducing a structural change that leads to the receptor's active state, which in turn activates associated intracellular signaling pathways. | ||||||