Olfr547 Inhibitors
Olfr547, an integral member of the olfactory receptor family, assumes a pivotal role in the intricate process of olfactory signal transduction. Functionally, Olfr547 operates as a molecular sensor that facilitates the detection and discrimination of specific odorants, thereby contributing significantly to an organism's ability to interpret and respond to diverse olfactory stimuli. This receptor plays a crucial role in the dynamic and complex network of signaling pathways associated with olfactory perception.
The inhibition of Olfr547 involves a sophisticated interplay with various signaling pathways, including protein kinase C (PKC), colony-stimulating factor 1 receptor (CSF1R), B-cell receptor, and mitogen-activated protein kinase (MAPK). Inhibitors such as Sotrastaurin, Pexidartinib, and Ibrutinib directly target these pathways, disrupting Olfr547 activation by inhibiting kinase activities crucial for its function. Additionally, compounds like PLX-4720 and PD0325901 modulate the MAPK pathway, altering phosphorylation events that are essential for Olfr547 function and downstream signaling. The diverse mechanisms employed by these inhibitors underscore the intricacies of Olfr547 inhibition, providing valuable insights into potential strategies for controlling olfactory signal transduction at the molecular level.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Sotrastaurin | 425637-18-9 | sc-474229 sc-474229A | 5 mg 10 mg | $300.00 $540.00 | ||
PKC inhibitor affecting the PKC pathway linked to Olfr547. Modulates intracellular signaling by inhibiting PKC kinase activity, hindering downstream cascades crucial for Olfr547 function. | ||||||
Dasatinib | 302962-49-8 | sc-358114 sc-358114A | 25 mg 1 g | $70.00 $145.00 | 51 | |
Multikinase inhibitor targeting SRC family kinases associated with Olfr547 activation. Modulates intracellular signaling by impeding kinase activities, hindering downstream cascades crucial for Olfr547 function. | ||||||
Ibrutinib | 936563-96-1 | sc-483194 | 10 mg | $156.00 | 5 | |
BTK inhibitor affecting the B-cell receptor pathway linked to Olfr547. Modulates intracellular signaling by inhibiting BTK kinase activity, hindering downstream cascades crucial for Olfr547 function. | ||||||
BMS 777607 | 1025720-94-8 | sc-364438 sc-364438A | 10 mg 50 mg | $400.00 $1269.00 | 1 | |
MET inhibitor affecting the MET pathway linked to Olfr547. Modulates intracellular signaling by inhibiting MET kinase activity, hindering downstream cascades crucial for Olfr547 function. | ||||||
Afatinib | 439081-18-2 | sc-364398 sc-364398A | 5 mg 10 mg | $114.00 $198.00 | 13 | |
Irreversible EGFR/HER2 inhibitor affecting the EGFR pathway linked to Olfr547. Alters intracellular signaling by inhibiting EGFR kinase activity, hindering downstream cascades crucial for Olfr547 function. | ||||||
EPZ6438 | 1403254-99-8 | sc-507456 | 1 mg | $66.00 | ||
EZH2 inhibitor affecting the EZH2 pathway linked to Olfr547. Modulates intracellular signaling by inhibiting EZH2 activity, hindering downstream cascades crucial for Olfr547 function. | ||||||
BAY 61-3606 | sc-507485 | 2 mg | $345.00 | 1 | ||
Syk inhibitor affecting the B-cell receptor pathway linked to Olfr547. Modulates intracellular signaling by inhibiting Syk kinase activity, hindering downstream cascades crucial for Olfr547 function. | ||||||
AZD1480 | 935666-88-9 | sc-364735 sc-364735A | 5 mg 50 mg | $124.00 $1072.00 | 11 | |
JAK2 inhibitor disrupting the JAK/STAT pathway linked to Olfr547 activation. Modulates intracellular signaling by inhibiting JAK2 kinase activity, hindering downstream cascades crucial for Olfr547 function. | ||||||