Chemical activators of Olfr502, as proposed above, are based on the typical mechanisms of olfactory receptor activation. These include Isoamyl acetate, Benzaldehyde, and Cinnamaldehyde, which are thought to directly interact with Olfr502. Upon binding, these compounds likely induce a conformational change in the receptor, leading to activation of the G-protein-coupled receptor (GPCR) signaling pathway. This process usually results in the production of cyclic AMP, a crucial second messenger in olfactory signal transduction.
Other compounds, such as Eugenol, Limonene, and Anethole, are also theorized to function similarly by binding to Olfr502 and activating the GPCR pathway. Each of these chemicals has distinct molecular structures that allow for specific interactions with Olfr502, triggering receptor activation. This specificity is key to the diverse range of odor detection and recognition in the olfactory system. The proposed activation of Olfr502 by these chemicals highlights the intricate molecular dynamics involved in olfactory perception and the sophisticated nature of GPCR-mediated signal transduction in the olfactory system.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Isopentyl acetate | 123-92-2 | sc-250190 sc-250190A | 100 ml 500 ml | $105.00 $221.00 | ||
Isopentyl acetate, known for its banana-like aroma, might activate Olfr502 by binding to its ligand-binding domain, initiating a conformational change that triggers GPCR signaling, leading to an increase in intracellular cyclic AMP. | ||||||
Cinnamic Aldehyde | 104-55-2 | sc-294033 sc-294033A | 100 g 500 g | $102.00 $224.00 | ||
Cinnamic Aldehyde, characterized by its cinnamon aroma, may activate Olfr502 by binding to its active site, triggering GPCR-mediated signaling pathways and resulting in an elevation of cyclic AMP levels. | ||||||
Eugenol | 97-53-0 | sc-203043 sc-203043A sc-203043B | 1 g 100 g 500 g | $31.00 $61.00 $214.00 | 2 | |
Eugenol, known for its clove-like scent, could activate Olfr502 through direct receptor interaction, leading to GPCR activation and a subsequent increase in cyclic AMP, crucial for olfactory signal transduction. | ||||||
D-Limonene | 5989-27-5 | sc-205283 sc-205283A | 100 ml 500 ml | $82.00 $126.00 | 3 | |
D-Limonene, with a citrus scent, might activate Olfr502 by interacting with its ligand-binding domain, initiating GPCR signaling and leading to increased cyclic AMP production, essential for olfactory signal processing. | ||||||
trans-Anethole | 4180-23-8 | sc-253727 | 1 ml | $27.00 | 1 | |
trans-Anethole, characterized by its licorice-like aroma, may activate Olfr502 through direct binding, triggering GPCR signaling pathways, and increasing cyclic AMP levels, vital for olfactory signal transduction. | ||||||
Vanillin | 121-33-5 | sc-251423 sc-251423A | 100 g 500 g | $43.00 $122.00 | 1 | |
Vanillin, known for its vanilla scent, could activate Olfr502 by binding to its active site, initiating GPCR-mediated signaling and resulting in increased cyclic AMP production. | ||||||
Ethyl butyrate | 105-54-4 | sc-214986 sc-214986A | 1 kg 4 kg | $100.00 $210.00 | ||
Ethyl butyrate, with a fruity scent, might interact with Olfr502, activating the receptor and leading to GPCR pathway initiation, resulting in an elevation of cyclic AMP levels, essential for olfactory signaling. | ||||||
(±)-Menthol | 89-78-1 | sc-250299 sc-250299A | 100 g 250 g | $38.00 $67.00 | ||
Menthol, characterized by its minty aroma, could activate Olfr502 by directly interacting with the receptor, leading to GPCR activation and subsequent cyclic AMP elevation, crucial for olfactory signal processing. | ||||||
Geraniol | 106-24-1 | sc-235242 sc-235242A | 25 g 100 g | $44.00 $117.00 | ||
Geraniol, with a floral scent, may bind to Olfr502, activating the receptor and initiating GPCR signaling, resulting in increased cyclic AMP levels, vital for olfactory signal transduction. | ||||||
α-Pinene | 80-56-8 | sc-233784 sc-233784A | 5 ml 250 ml | $51.00 $113.00 | 2 | |
(-)-α-Pinene, known for its pine-like aroma, might activate Olfr502 by binding to its ligand-binding domain, triggering GPCR-mediated signaling and an increase in cyclic AMP. | ||||||