Olfr486 Activators
Chemical activators of Olfr486, as proposed in this list, are based on the typical activation mechanisms of olfactory receptors. These chemicals, such as Ethyl acetate, Isoamyl alcohol, and Butyl butyrate, are hypothesized to interact directly with Olfr486, a G-protein-coupled receptor (GPCR). Upon binding to Olfr486, these compounds are likely to induce a conformational change in the receptor, initiating a cascade of intracellular events characteristic of GPCR activation. This process typically results in the production of cyclic AMP, a critical second messenger in olfactory signal transduction. The elevation in cyclic AMP is essential for converting the chemical signal into a neural signal, facilitating olfactory perception.
Other compounds like Amyl butyrate, Hexyl acetate, and Benzyl alcohol are also hypothesized to function similarly, binding to Olfr486 and activating the GPCR pathway. Each of these chemicals has a unique molecular structure that allows specific interaction with Olfr486, triggering the receptor's activation. This specificity is vital for the diverse range of odor detection and recognition in the olfactory system. The proposed activation of Olfr486 by these chemicals underscores the intricate molecular dynamics involved in olfactory perception and the sophisticated nature of GPCR-mediated signal transduction in the olfactory system.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Ethyl Acetate, HPLC | 141-78-6 | sc-360247 sc-360247A | 1 L 4 L | $120.00 $320.00 | ||
Ethyl acetate, with a fruity aroma, may activate Olfr486 by direct binding, potentially inducing a conformational change in the receptor and initiating the GPCR signaling pathway, leading to increased cyclic AMP levels, crucial for olfactory signal transduction. | ||||||
3-Methyl-1-butanol | 123-51-3 | sc-231818 sc-231818A | 500 ml 1 L | $70.00 $93.00 | ||
3-Methyl-1-butanol, found in bananas, could activate Olfr486 through direct interaction with its ligand-binding domain, triggering the GPCR pathway and resulting in elevated cyclic AMP, essential for olfactory signal processing. | ||||||
Butyl butyrate | 109-21-7 | sc-239439 | 250 ml | $210.00 | ||
Butyl butyrate, with a pineapple-like scent, may bind directly to Olfr486, inducing a structural change in the receptor. This activates the GPCR mechanism, leading to increased cyclic AMP and olfactory signal transduction. | ||||||
Hexyl acetate | 142-92-7 | sc-215149 sc-215149A | 25 ml 500 ml | $32.00 $57.00 | ||
Hexyl acetate, with a sweet fruity aroma, could activate Olfr486 by direct binding, leading to GPCR pathway activation and subsequent increase in cyclic AMP, crucial for olfactory signal transmission. | ||||||
Benzyl alcohol | 100-51-6 | sc-326216B sc-326216 sc-326216A | 250 ml 1 L 5 L | $31.00 $102.00 $408.00 | ||
Benzyl alcohol, possessing a mild floral scent, may activate Olfr486 through direct binding to the receptor, triggering the GPCR signaling pathway and resulting in increased cyclic AMP, essential for olfactory signal transduction. | ||||||
Ethyl hexanoate | 123-66-0 | sc-235049 | 5 ml | $50.00 | ||
Ethyl hexanoate, known for its pineapple-like aroma, might activate Olfr486 through direct receptor binding, triggering the GPCR mechanism and increasing cyclic AMP levels, crucial for olfactory signal transduction. | ||||||
Propyl acetate | 109-60-4 | sc-250792 | 500 ml | $20.00 | ||
Propyl acetate, with a fruity aroma, could activate Olfr486 by direct interaction, initiating the GPCR pathway and leading to an elevation in cyclic AMP, important for olfactory signal processing. | ||||||
Methyl butyrate | 623-42-7 | sc-215339 sc-215339A | 1 kg 5 kg | $95.00 $210.00 | ||
Methyl butyrate, present in apples, potentially activates Olfr486 by direct binding, leading to GPCR pathway activation and a subsequent rise in cyclic AMP, essential for olfactory signaling. | ||||||
Ethyl propionate | 105-37-3 | sc-214997 sc-214997A | 25 ml 500 ml | $15.00 $39.00 | ||
Ethyl propionate, with a fruity and rum-like scent, may activate Olfr486 through direct interaction with the receptor, initiating the GPCR signaling pathway and resulting in increased cyclic AMP, important for olfactory signal transduction. | ||||||
Butyl acetate | 123-86-4 | sc-214637 sc-214637A | 1 ml 5 ml | $20.00 $77.00 | ||
Butyl acetate, common in apples, could activate Olfr486 by binding to its active site, inducing the GPCR pathway and subsequent increase in cyclic AMP, crucial for the transmission of olfactory signals. | ||||||