Olfr483 Activators
Chemical activators of Olfr483 are proposed based on their potential interaction with the olfactory receptor and the initiation of the G-protein-coupled receptor (GPCR) signaling pathway. Compounds like Amyl acetate, Eucalyptol, and D-Limonene are hypothesized to bind directly to Olfr483, inducing a change in the receptor's conformation. This interaction is thought to trigger the GPCR pathway, leading to an increase in cyclic AMP, a critical second messenger in the olfactory system. The elevation of cyclic AMP levels is vital for converting the chemical signal into a neural signal, which is then transmitted to the brain for olfactory perception.
Other chemicals in this list, such as Ethyl hexanoate, Methyl anthranilate, and Nonanal, are also considered potential activators of Olfr483 through a similar mechanism. Their unique molecular structures allow for specific interactions with Olfr483, hypothesized to facilitate the receptor's activation. This process highlights the complex and specialized nature of olfactory receptors in detecting a diverse array of scents. The interaction of these chemicals with Olfr483 underscores the intricate molecular dynamics involved in olfactory perception and the sophisticated nature of GPCR-mediated signal transduction in the olfactory system.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Pentyl acetate | 628-63-7 | sc-215691 | 250 ml | $66.00 | ||
Pentyl acetate, with a banana-like aroma, may activate Olfr483 by direct binding, potentially inducing a conformational change in the receptor and initiating the GPCR signaling pathway, leading to increased cyclic AMP levels, crucial for olfactory signal transduction. | ||||||
1,8-Cineole | 470-82-6 | sc-485261 | 25 ml | $44.00 | 2 | |
1,8-Cineole, found in eucalyptus oil, could activate Olfr483 through direct interaction with its ligand-binding domain, triggering the GPCR pathway and resulting in elevated cyclic AMP, essential for olfactory signal processing. | ||||||
D-Limonene | 5989-27-5 | sc-205283 sc-205283A | 100 ml 500 ml | $84.00 $129.00 | 3 | |
D-Limonene, with a citrus scent, may bind directly to Olfr483, inducing a structural change in the receptor. This activates the GPCR mechanism, leading to increased cyclic AMP and olfactory signal transduction. | ||||||
Ethyl hexanoate | 123-66-0 | sc-235049 | 5 ml | $51.00 | ||
Ethyl hexanoate, common in pineapples, might activate Olfr483 by binding to its ligand-binding site. This interaction can trigger the GPCR cascade, increasing cyclic AMP levels, essential for olfactory signaling. | ||||||
Nonanal | 124-19-6 | sc-257926 | 1 g | $67.00 | ||
Nonanal, present in citrus, may activate Olfr483 through direct binding to the receptor, triggering the GPCR signaling pathway and resulting in increased cyclic AMP, essential for olfactory signal transduction. | ||||||
Octyl acetate | 112-14-1 | sc-236244 | 5 g | $24.00 | ||
Octyl acetate, with a fruity aroma, could activate Olfr483 by direct interaction, initiating the GPCR pathway and leading to an elevation in cyclic AMP, important for olfactory signal processing. | ||||||
2-Phenylethanol | 60-12-8 | sc-238198 | 250 ml | $69.00 | ||
2-Phenylethanol, found in roses, might activate Olfr483 through direct receptor binding, triggering the GPCR mechanism and increasing cyclic AMP levels, crucial for olfactory signal transduction. | ||||||
α-Pinene | 80-56-8 | sc-233784 sc-233784A | 5 ml 250 ml | $52.00 $115.00 | 2 | |
α-Pinene, a major component of pine resin, is likely to activate Olfr483 via direct binding, initiating the GPCR signaling pathway. This leads to an increase in cyclic AMP, facilitating the activation of olfactory signal transduction mechanisms. | ||||||
beta-Ionone | 14901-07-6 | sc-291976 | 25 ml | $83.00 | ||
β-Ionone, with a violet-like aroma, may activate Olfr483 through direct interaction, inducing the GPCR pathway, resulting in increased cyclic AMP, crucial for olfactory signal processing. | ||||||
Citral | 5392-40-5 | sc-252620 | 1 kg | $212.00 | ||
Citral, present in lemongrass, could activate Olfr483 by binding to its active site, initiating the GPCR cascade. This leads to increased cyclic AMP levels, essential for the transmission of olfactory signals. | ||||||