Olfr319 Activators
Chemical activators of Olfr319 include a variety of compounds that interact with the protein to initiate a cascade of signaling events within the cell. Acetophenone, Benzaldehyde, and Cinnamaldehyde are aromatic chemicals that bind directly to the odorant receptor site of Olfr319, which causes a conformational change in the protein structure. This change is crucial as it leads to the activation of the G-protein coupled receptor (GPCR) pathway, which is a classic mechanism of signal transduction for olfactory receptors. Ethyl Vanillin and Eugenol also serve as activators by engaging with the ligand-binding domain of Olfr319, inducing essential conformational shifts that trigger the GPCR pathway, leading to the activation of the receptor. Similarly, Isoeugenol and Limonene bind to Olfr319 and induce structural changes that activate the associated G-protein signaling pathway linked to the receptor's function.
Methyl Salicylate, Phenethyl Alcohol, and Vanillin activate Olfr319 by direct interaction with its binding site, triggering a conformational change that is necessary for the activation of the downstream GPCR signaling cascade. This demonstrates the specificity of the ligand-receptor interaction that is fundamental to the function of olfactory receptors like Olfr319. Furthermore, compounds such as Alpha-Ionone and Beta-Ionone act as activators by binding to the receptor's ligand-binding site, which prompts a conformational shift, stimulating the G protein-coupled signaling pathway. This consistent mechanism of binding and activating the GPCR pathway underscores the direct role these chemicals play in the functional activation of Olfr319, elucidating the molecular dynamics involved in olfactory perception at the receptor level.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Acetophenone | 98-86-2 | sc-239189 | 5 g | $20.00 | ||
Acetophenone, through its aromatic character, activates Olfr319 by binding directly to the odorant receptor site, causing a conformational change that leads to activation of the G-protein coupled receptor pathway and subsequent signal transduction. | ||||||
Cinnamic Aldehyde | 104-55-2 | sc-294033 sc-294033A | 100 g 500 g | $104.00 $228.00 | ||
Cinnamaldehyde binds to Olfr319, causing a conformational alteration that activates the linked G protein, thereby activating the receptor and its downstream signaling pathways. | ||||||
3-Ethoxy-4-hydroxybenzaldehyde | 121-32-4 | sc-238538 | 100 g | $31.00 | ||
Ethyl Vanillin activates Olfr319 by engaging with its ligand-binding domain, which in turn induces a conformational shift essential for triggering the GPCR pathway and activating the receptor. | ||||||
Eugenol | 97-53-0 | sc-203043 sc-203043A sc-203043B | 1 g 100 g 500 g | $32.00 $62.00 $218.00 | 2 | |
Eugenol serves as an activator of Olfr319 by fitting into its binding site, which leads to a conformational change and activation of the associated intracellular GPCR signaling mechanisms. | ||||||
Isoeugenol | 97-54-1 | sc-250186 sc-250186A | 5 g 100 g | $63.00 $53.00 | ||
Isoeugenol activates Olfr319 by interacting with its specific binding site, inducing a structural change that activates the G-protein signaling pathway linked to the receptor. | ||||||
Dipentene | 138-86-3 | sc-252747 | 4 L | $120.00 | ||
Limonene binds and activates Olfr319 through a conformational shift that stimulates the G-protein coupled receptor pathway, leading to the activation of the receptor. | ||||||
Methyl Salicylate | 119-36-8 | sc-204802 sc-204802A | 250 ml 500 ml | $47.00 $70.00 | ||
Methyl Salicylate activates Olfr319 by direct interaction with its binding site, which triggers a conformational change and subsequent activation of the GPCR signaling cascade. | ||||||
2-Phenylethanol | 60-12-8 | sc-238198 | 250 ml | $69.00 | ||
Phenethyl Alcohol activates Olfr319 by binding to its ligand-specific site, prompting a conformational change that leads to the activation of G-protein mediated signal transduction mechanisms. | ||||||
Vanillin | 121-33-5 | sc-251423 sc-251423A | 100 g 500 g | $44.00 $124.00 | 1 | |
Vanillin activates Olfr319 by ligand-receptor interaction that induces a conformational change in the receptor, resulting in the activation of the downstream GPCR signaling pathway. | ||||||
α-Ionone | 127-41-3 | sc-239157 | 100 g | $75.00 | ||
Alpha-Ionone activates Olfr319 by binding to the receptor's ligand-binding site, triggering a conformational change that stimulates the G protein-coupled signaling pathway inherent to the receptor's function. | ||||||