Olfr1247 Activators
Olfr1247 Activators encompass a range of chemical compounds that indirectly augment the functional activity of this protein through diverse signaling pathways and neural mechanisms. Compounds like Icilin and (-)-Menthol, through their activation of TRPM8 channels, modulate sensory neural pathways, potentially enhancing Olfr1247's role in olfactory perception by altering the neural signaling environment. Similarly, Eugenol's interaction with TRPV3 and Capsaicin's effect on TRPV1 channels impact the activity of olfactory sensory neurons, thereby indirectly influencing Olfr1247's sensitivity or responsiveness within the olfactory signaling system. Cinnamic Aldehyde and Allyl isothiocyanate activate TRPA1 channels, and their impact on sensory neuron signaling could enhance Olfr1247's function in olfactory processing. Furthermore, the modulation of GABAergic and glutamatergic neurotransmission by Ethanol and the influence of Acetylcholine on cholinergic receptors potentially affect the neural circuitry in a manner that enhances olfactory receptor activity.
In addition, Histamine, free base, through its action on H1 receptors, and Sodium Fluoride's activation of G-proteins, integral in olfactory signal transduction, contribute to modulating neural signaling pathways that may influence olfactory receptor activity. The interaction of Bitter and Sweet compounds, exemplified by Quinine and Sucrose, with taste receptors also plays a role in modulating olfactory neuron responses, potentially enhancing Olfr1247's involvement in the integrated sensory perception. These diverse mechanisms, ranging from the modulation of temperature-sensitive ion channels to the influence on neurotransmitter systems and sensory receptor interactions, collectively contribute to the indirect enhancement of Olfr1247's functionality in the olfactory system. This intricate interplay of neural and sensory signaling underscores the multifaceted regulation of olfactory receptor proteins like Olfr1247, highlighting the complex network of interactions that govern sensory perception.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Icilin | 36945-98-9 | sc-201557 sc-201557A | 10 mg 50 mg | $89.00 $252.00 | 9 | |
Icilin activates transient receptor potential channels (TRPM8), involved in cold sensing. This activation influences sensory neural pathways and potentially enhances olfactory receptor activity in olfactory neurons by modulating the neural signaling environment. | ||||||
Eugenol | 97-53-0 | sc-203043 sc-203043A sc-203043B | 1 g 100 g 500 g | $31.00 $61.00 $214.00 | 2 | |
Eugenol interacts with TRPV3, a thermosensitive ion channel. This interaction can lead to altered neural activity in olfactory sensory neurons, indirectly enhancing olfactory receptor sensitivity or response within the olfactory signaling pathway. | ||||||
Capsaicin | 404-86-4 | sc-3577 sc-3577C sc-3577D sc-3577A | 50 mg 250 mg 500 mg 1 g | $94.00 $173.00 $255.00 $423.00 | 26 | |
Capsaicin activates TRPV1 channels, impacting nociceptive neurons. This activation could indirectly enhance the functionality in the olfactory sensory network through modulation of sensory neuron excitability. | ||||||
(−)-Menthol | 2216-51-5 | sc-202705 sc-202705A | 1 g 50 g | $20.00 $40.00 | 2 | |
(-)-Menthol activates TRPM8 channels, similarly to Icilin. This activation modulates sensory neuron activity, potentially augmenting the functional response in the olfactory system. | ||||||
Cinnamic Aldehyde | 104-55-2 | sc-294033 sc-294033A | 100 g 500 g | $102.00 $224.00 | ||
Cinnamic Aldehyde activates TRPA1 channels, involved in sensory neuron signaling. This activation might enhance roles in olfactory perception by modulating sensory neuron pathways. | ||||||
Allyl isothiocyanate | 57-06-7 | sc-252361 sc-252361A sc-252361B | 5 g 100 g 500 g | $43.00 $66.00 $117.00 | 3 | |
Known for its presence in mustard oil, Allyl isothiocyanate activates TRPA1 channels, affecting sensory neuron signaling. This could indirectly enhance olfactory receptor activity through its effects on the sensory neural circuitry. | ||||||
Histamine, free base | 51-45-6 | sc-204000 sc-204000A sc-204000B | 1 g 5 g 25 g | $92.00 $277.00 $969.00 | 7 | |
Histamine, in its free base form, acts on H1 receptors and can modulate neural signaling. This action potentially activates olfactory receptor activities in olfactory pathways. | ||||||
Sodium Fluoride | 7681-49-4 | sc-24988A sc-24988 sc-24988B | 5 g 100 g 500 g | $39.00 $45.00 $98.00 | 26 | |
Sodium Fluoride activates G-proteins, crucial in olfactory signal transduction. This activation may indirectly enhance olfactory receptor activity by modulating the G-protein-coupled receptor signaling pathway. | ||||||
Quinine | 130-95-0 | sc-212616 sc-212616A sc-212616B sc-212616C sc-212616D | 1 g 5 g 10 g 25 g 50 g | $77.00 $102.00 $163.00 $347.00 $561.00 | 1 | |
Bitter compounds like Quinine activate specific taste receptors, potentially modulating olfactory neuron responses. This could indirectly enhance olfactory receptor roles in the integrated sensory experience. | ||||||
Sucrose | 57-50-1 | sc-204311 sc-204311B sc-204311C sc-204311A | 0.5 kg 50 kg 100 kg 5 kg | $57.00 $1224.00 $1760.00 $195.00 | 6 | |
Sweet compounds such as Sucrose interact with taste receptors, potentially influencing olfactory pathways. This interaction might enhance olfactory receptor functions by modulating combined sensory perception. | ||||||