Olfr1045 Activators
Olfr1045 activators encompass a diverse range of chemical compounds, each uniquely contributing to the enhancement of this protein's functional activity through specific biochemical pathways. Acetophenone, for instance, engages Olfr1045 by fitting into its odorant receptor site, initiating a series of GPCR-mediated signals that escalate intracellular cAMP levels, a critical component for Olfr1045's signaling efficacy. Isoamyl Acetate, with its distinct binding to the ligand-specific domain, further amplifies this process, emphasizing the role of adenylate cyclase activation in Olfr1045's function. Similarly, Benzaldehyde and Eugenol, through their respective interactions with Olfr1045, potentiate the GPCR signaling cascade, underscoring the significance of cAMP and protein kinase A pathways in the receptor's operation. Vanillin and Citral, by engaging with Olfr1045, contribute to this synergistic enhancement, further solidifying the receptor's role in olfactory signaling.
In addition to these compounds, Anethole, Ethyl Vanillin, and Cinnamaldehyde play pivotal roles in activating Olfr1045 by binding to its active site and propelling GPCR-mediated pathways, predominantly influencing cAMP dynamics crucial for the receptor's function. Limonene, Menthol, and Methyl Salicylate extend this functional enhancement, each binding to Olfr1045 and triggering distinct but interconnected GPCR signaling routes that culminate in elevated cAMP production. This concerted action by these diverse molecules underscores the intricate network of biochemical pathways that converge on Olfr1045, highlighting its central role in olfactory signal transduction. Collectively, these activators not only elucidate the functional complexity of Olfr1045 but also demonstrate the receptor's integral position in the broader context of olfactory GPCR signaling, underlining the sophistication of sensory perception mechanisms at the molecular level.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Acetophenone | 98-86-2 | sc-239189 | 5 g | $20.00 | ||
Acetophenone interacts with Olfr1045 by binding to its odorant receptor site, thereby triggering a GPCR-mediated cascade. This leads to an increase in intracellular cAMP levels, directly enhancing Olfr1045's signaling capacity. | ||||||
Isopentyl acetate | 123-92-2 | sc-250190 sc-250190A | 100 ml 500 ml | $105.00 $221.00 | ||
Isoamyl Acetate activates Olfr1045 by binding to its ligand-binding domain. This action initiates GPCR signaling, notably the activation of adenylate cyclase, crucial for Olfr1045's functional activity. | ||||||
Eugenol | 97-53-0 | sc-203043 sc-203043A sc-203043B | 1 g 100 g 500 g | $31.00 $61.00 $214.00 | 2 | |
Eugenol interacts with Olfr1045, triggering GPCR-mediated signal transduction. This interaction stimulates pathways involving protein kinase A (PKA), which are integral to the activation and function of Olfr1045. | ||||||
Vanillin | 121-33-5 | sc-251423 sc-251423A | 100 g 500 g | $43.00 $122.00 | 1 | |
Vanillin binds to the ligand-specific region of Olfr1045, promoting GPCR signaling. This enhances the olfactory signaling cascade, particularly through cAMP and PKA pathways, vital for Olfr1045 activation. | ||||||
Citral | 5392-40-5 | sc-252620 | 1 kg | $212.00 | ||
Citral's interaction with Olfr1045 activates GPCR pathways, leading to increased cAMP production. This activation is critical for the functional signaling of Olfr1045 in olfactory processes. | ||||||
trans-Anethole | 4180-23-8 | sc-253727 | 1 ml | $27.00 | 1 | |
Anethole binds to Olfr1045, initiating GPCR signaling. This binding boosts intracellular signaling mechanisms, particularly through the cAMP pathway, crucial for Olfr1045's functional activation. | ||||||
3-Ethoxy-4-hydroxybenzaldehyde | 121-32-4 | sc-238538 | 100 g | $31.00 | ||
Ethyl Vanillin, by binding to Olfr1045, enhances GPCR-mediated signaling pathways. This interaction significantly increases cAMP levels, a key step in the functional activation of Olfr1045. | ||||||
Cinnamic Aldehyde | 104-55-2 | sc-294033 sc-294033A | 100 g 500 g | $102.00 $224.00 | ||
Cinnamaldehyde activates Olfr1045 through its binding to the receptor's active site, initiating GPCR signaling. This leads to a cascade of intracellular events, predominantly through cAMP, vital for Olfr1045 activation. | ||||||
D-Limonene | 5989-27-5 | sc-205283 sc-205283A | 100 ml 500 ml | $82.00 $126.00 | 3 | |
Limonene's interaction with Olfr1045 triggers a GPCR-mediated signaling pathway. This enhances intracellular cAMP production, which is fundamental for the functional activity of Olfr1045. | ||||||
(±)-Menthol | 89-78-1 | sc-250299 sc-250299A | 100 g 250 g | $38.00 $67.00 | ||
Menthol binds to Olfr1045, activating GPCR signaling mechanisms. This interaction boosts cAMP levels in cells, playing a crucial role in the functional activation of Olfr1045. | ||||||