Olfr10 Activators
Olfr10 Activators are a chemical class comprising various organic compounds that can interact with the olfactory receptor Olfr10, leading to its activation. These activators typically possess distinct odorous properties and include a range of different aromatic and volatile molecules such as aldehydes, terpenes, esters, and phenols. The mode of action of these chemicals involves binding to the ligand-binding domain of Olfr10, which is a G-protein coupled receptor (GPCR). Upon ligand binding, conformational changes in the receptor are induced, leading to the activation of G-proteins. This activation then triggers a cascade of intracellular events that result in a neuronal response, ultimately contributing to the perception of smell.
The specificity of each activator for Olfr10 is based on the precise molecular interactions between the ligand and the receptor, which are shaped by the chemical structure of the activator. The structural diversity among Olfr10 activators reflects the broad range of scents that the human olfactory system can detect. These activators are not simply binding partners but are integral to the process of olfactory discrimination, enabling the differentiation of a wide spectrum of odorants. The functional mechanism of these activators is crucial to understanding how scent molecules like Olfr10 work.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Cinnamic Aldehyde | 104-55-2 | sc-294033 sc-294033A | 100 g 500 g | $104.00 $228.00 | ||
Cinnamaldehyde is an organic compound that gives cinnamon its flavor and odor. This aldehyde can modulate the olfactory system by binding to various olfactory receptors, such as Olfr10, potentially leading to activation. The interaction between cinnamaldehyde and Olfr10 can initiate a signal transduction cascade resulting in a sensory response. | ||||||
Eugenol | 97-53-0 | sc-203043 sc-203043A sc-203043B | 1 g 100 g 500 g | $32.00 $62.00 $218.00 | 2 | |
Eugenol is a key component of clove oil and has a spicy, clove-like aroma. It has been shown to interact with olfactory receptors and could specifically activate Olfr10 by binding to its ligand-binding domain, which would then trigger G-protein coupled receptor signaling pathways within olfactory sensory neurons. | ||||||
Isopentyl acetate | 123-92-2 | sc-250190 sc-250190A | 100 ml 500 ml | $107.00 $225.00 | ||
Isoamyl acetate has a strong odor similar to bananas and pears. It is known to interact with certain olfactory receptors, and its interaction with Olfr10 could cause conformational changes leading to the activation of downstream signaling pathways related to olfactory perception. | ||||||
Anethole | 104-46-1 | sc-481571A sc-481571 | 10 g 100 g | $576.00 $316.00 | ||
Anethole is an aromatic compound with a sweet, licorice-like aroma, found in anise and fennel. It likely activates Olfr10 by binding to the receptor's active site, prompting a G-protein-coupled response that can culminate in sensory neuron activation. | ||||||
Citral | 5392-40-5 | sc-252620 | 1 kg | $212.00 | ||
Citral is a component of lemongrass oil and has a citrus scent. It is known to activate olfactory receptors, and its interaction with Olfr10 might result in the receptor's activation through the typical G-protein signaling cascade associated with olfactory transduction. | ||||||
(±)-Menthol | 89-78-1 | sc-250299 sc-250299A | 100 g 250 g | $39.00 $68.00 | ||
Menthol is a compound found in peppermint with a characteristic minty odor. Its activation of Olfr10 is hypothesized to occur through direct binding to the receptor, which would trigger the associated G-protein signaling mechanisms involved in olfactory processing. | ||||||
Ethyl butyrate | 105-54-4 | sc-214986 sc-214986A | 1 kg 4 kg | $100.00 $210.00 | ||
Ethyl butyrate has a fruity odor, similar to pineapples. It is presumed to activate Olfr10 by engaging with the receptor's ligand-binding domain, thus initiating the olfactory signaling cascade. | ||||||
Vanillin | 121-33-5 | sc-251423 sc-251423A | 100 g 500 g | $44.00 $124.00 | 1 | |
Vanillin is the primary component of the extract of the vanilla bean. It can interact with olfactory receptors, and its binding to Olfr10 is expected to activate the receptor and its downstream signaling pathways. | ||||||
Dipentene | 138-86-3 | sc-252747 | 4 L | $120.00 | ||
Limonene is a prominent compound in citrus fruit peels. It can bind to and activate several olfactory receptors, and its interaction with Olfr10 would likely involve receptor activation that leads to a sensory signal. | ||||||
Geraniol | 106-24-1 | sc-235242 sc-235242A | 25 g 100 g | $45.00 $119.00 | ||
Geraniol is present in rose oil and palmarosa oil, with a sweet floral odor. It is capable of activating olfactory receptors, and its activation of Olfr10 would be through receptor-ligand interaction, initiating the G-protein signal transduction pathway. | ||||||