OIP5 Activators
OIP5 activators are a group of chemicals that indirectly modulate the activity or function of OIP5 through their impact on cell cycle regulation, centromere function, and related cellular processes. OIP5 is involved in critical aspects of cell division, and the chemicals listed here influence various stages and mechanisms of the cell cycle, impacting OIP5's function.
Microtubule-targeting agents like Paclitaxel, Nocodazole, Colchicine, and Vinblastine play a significant role in cell cycle regulation by affecting microtubule dynamics. These dynamics are crucial for the proper function of the mitotic spindle and chromosome segregation, processes where OIP5 might play a role. By stabilizing or destabilizing microtubules, these agents can indirectly influence the activity of OIP5.5-Fluorouracil, Hydroxyurea, and Gemcitabine impact DNA replication, a critical phase of the cell cycle. The inhibition of DNA synthesis can lead to cell cycle arrest, which may indirectly affect OIP5 function, given its involvement in cell cycle regulation.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $41.00 $74.00 $221.00 $247.00 $738.00 $1220.00 | 39 | |
Paclitaxel stabilizes microtubules, which are essential for cell division and could influence processes related to OIP5 function. | ||||||
Roscovitine | 186692-46-6 | sc-24002 sc-24002A | 1 mg 5 mg | $94.00 $265.00 | 42 | |
Roscovitine is a cyclin-dependent kinase inhibitor, impacting cell cycle regulation and possibly influencing OIP5 activity. | ||||||
Fluorouracil | 51-21-8 | sc-29060 sc-29060A | 1 g 5 g | $37.00 $152.00 | 11 | |
5-Fluorouracil inhibits thymidylate synthase, affecting DNA synthesis and the cell cycle, potentially impacting OIP5. | ||||||
Bleomycin | 11056-06-7 | sc-507293 | 5 mg | $275.00 | 5 | |
Bleomycin causes DNA damage, leading to cell cycle arrest, which may indirectly affect OIP5 function. | ||||||
Vinblastine | 865-21-4 | sc-491749 sc-491749A sc-491749B sc-491749C sc-491749D | 10 mg 50 mg 100 mg 500 mg 1 g | $102.00 $235.00 $459.00 $1749.00 $2958.00 | 4 | |
Vinblastine inhibits microtubule formation, affecting cell cycle and potentially influencing OIP5. | ||||||
Hydroxyurea | 127-07-1 | sc-29061 sc-29061A | 5 g 25 g | $78.00 $260.00 | 18 | |
Hydroxyurea inhibits ribonucleotide reductase, leading to DNA synthesis inhibition and potential impact on OIP5. | ||||||
2′-Deoxy-2′,2′-difluorocytidine | 95058-81-4 | sc-275523 sc-275523A | 1 g 5 g | $56.00 $128.00 | ||
Gemcitabine is a nucleoside analog that inhibits DNA synthesis, potentially affecting cell cycle processes relevant to OIP5. | ||||||
Doxorubicin | 23214-92-8 | sc-280681 sc-280681A | 1 mg 5 mg | $176.00 $426.00 | 43 | |
Doxorubicin intercalates DNA and inhibits topoisomerase II, affecting DNA replication and potentially OIP5 function. | ||||||
Mitomycin C | 50-07-7 | sc-3514A sc-3514 sc-3514B | 2 mg 5 mg 10 mg | $66.00 $101.00 $143.00 | 85 | |
Mitomycin C is an alkylating agent that can cause DNA crosslinking and potentially influence OIP5 activity. | ||||||