Date published: 2026-4-5

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Nrf1 Antibodies

Santa Cruz Biotechnology provides a broad selection of Nrf1 monoclonal antibodies for research focused on understanding Nuclear factor erythroid 2-related factor 1 (Nrf1) protein functions. Nrf1 monoclonal antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Nuclear factor erythroid 2-related factor 1 functions as a transcription factor with a crucial role in cellular responses to oxidative stress and regulation of antioxidant genes. Nrf1 maintains cellular homeostasis and protects cells from damage caused by reactive oxygen species. Research has shown that Nrf1 activity significantly influences various diseases, including neurodegenerative disorders and cancer. Understanding Nrf1's molecular mechanisms and regulatory pathways can provide valuable insights into disease progression and potential therapeutic strategies. Investigating Nrf1's role in oxidative stress response pathways continues to reveal new aspects of cellular defense mechanisms. Current research highlights Nrf1's importance in maintaining cellular health and disease prevention. Santa Cruz Biotechnology monoclonal antibodies enable researchers worldwide to advance scientific understanding of Nrf1's role in human health and disease.

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Nrf1 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

Nrf1 Antibody (G-5)

sc-515360mouse IgG2b747-772 (h)WB, IP, IF, ELISAm, r, h
5
(3)

Nrf1 Antibody (H-4)

sc-28379mouse IgG2a κ191-475WB, IP, IF, IHC(P), ELISAm, r, h
25
(14)

Nrf1 Antibody (E-4)

sc-365651mouse IgG3 κ121-157 (h)WB, IP, IF, IHC(P), ELISAm, r, h
4
(3)

Nrf1 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Nrf1 CRISPR/Cas9 KO Plasmid (h2)

sc-401053-KO-2hGene KnockoutGFP0
(0)

Nrf1 HDR Plasmid (h2)

sc-401053-HDR-2hHomology Directed RepairPuromycin0
(0)

Nrf1 Double Nickase Plasmid (h)

sc-401053-NIChGene KnockoutPuromycin0
(0)

Nrf1 Double Nickase Plasmid (h2)

sc-401053-NIC-2hGene KnockoutPuromycin0
(0)

Nrf1 CRISPR/Cas9 KO Plasmid (m)

sc-421868mGene KnockoutGFP0
(0)

Nrf1 HDR Plasmid (m)

sc-421868-HDRmHomology Directed RepairPuromycin0
(0)

Nrf1 CRISPR Activation Products

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Nrf1 CRISPR Activation Plasmid (h)

sc-401053-ACThGene ActivationPuro, Blast, Hygro0
(0)

Nrf1 CRISPR Activation Plasmid (m)

sc-421868-ACTmGene ActivationPuro, Blast, Hygro0
(0)

Nrf1 CRISPR Activation Plasmid (m2)

sc-421868-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

Nrf1 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Nrf1 siRNA (h)

sc-43575hGene SilencingN/A
6
(0)

Nrf1 shRNA Plasmid (h)

sc-43575-SHhGene SilencingPuromycin
6
(0)

Nrf1 shRNA (h) Lentiviral Particles

sc-43575-VhGene SilencingPuromycin
6
(0)

Nrf1 siRNA (m)

sc-43576mGene SilencingN/A
3
(1)

Nrf1 shRNA Plasmid (m)

sc-43576-SHmGene SilencingPuromycin
3
(1)

Nrf1 shRNA (m) Lentiviral Particles

sc-43576-VmGene SilencingPuromycin
3
(1)