Date published: 2026-5-7

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Notch 1 Antibodies

Santa Cruz Biotechnology provides a broad selection of Notch 1 monoclonal antibodies for research focused on understanding the Notch signaling pathway. Notch 1 monoclonal antibodies are compatible with multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Notch 1 is a central component of the Notch signaling pathway, which plays a vital role in cell differentiation, proliferation, and apoptosis. The Notch signaling pathway is essential for various biological processes, including embryonic development and tissue homeostasis, and has been implicated in numerous diseases, including cancer. Understanding Notch 1 function is crucial for developing targeted therapies and advancing knowledge of cellular communication. Researchers worldwide rely on Notch 1 monoclonal antibodies to investigate signaling mechanisms and cellular responses. Advanced research techniques utilizing Notch 1 monoclonal antibodies enable deeper insights into developmental biology and disease progression. Current studies with Notch 1 monoclonal antibodies continue to reveal new aspects of cellular regulation and potential therapeutic targets. Santa Cruz Biotechnology monoclonal antibodies support the scientific community by facilitating breakthrough discoveries in Notch signaling research.

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Notch 1 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

Notch1 Antibody (A-8)

sc-376403mouse IgM κ2415-2453 (h)WB, IP, IF, IHC(P), ELISAm, r, h
50
(27)

Notch1 Antibody (mN1A)

sc-32745mouse IgG1 κ(m)WB, IPm, r, h
27
(13)

Notch1 Antibody (C-10)

sc-373891mouse IgG2b κ2433-2467 (h)WB, IP, IF, ELISAm, r, h
26
(7)

Notch1 Antibody (8G10)

sc-32756S. hamster IgG1299-1492 (m)WB, IP, IFm, r
8
(2)

Notch1 Antibody (E-4)

sc-373944mouse IgG2b κC-Terminal (h)WB, IP, IF, ELISAm, r, h
4
(3)

Notch1 Antibody (4i50)

sc-71719S. hamster IgG1299-1492 (m)WB, IP, IFm, r
4
(1)

Notch 1 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Notch1 CRISPR/Cas9 KO Plasmid (h2)

sc-400167-KO-2hGene KnockoutGFP0
(0)

Notch1 HDR Plasmid (h2)

sc-400167-HDR-2hHomology Directed RepairPuromycin0
(0)

Notch1 Double Nickase Plasmid (h)

sc-400167-NIChGene KnockoutPuromycin0
(0)

Notch1 Double Nickase Plasmid (h2)

sc-400167-NIC-2hGene KnockoutPuromycin0
(0)

Notch1 CRISPR/Cas9 KO Plasmid (m2)

sc-421930-KO-2mGene KnockoutGFP0
(0)

Notch1 Double Nickase Plasmid (m)

sc-421930-NICmGene KnockoutPuromycin0
(0)

Notch1 Double Nickase Plasmid (m2)

sc-421930-NIC-2mGene KnockoutPuromycin0
(0)

Notch 1 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Notch1 CRISPR Activation Plasmid (h)

sc-400167-ACThGene ActivationPuro, Blast, Hygro0
(0)

Notch1 Lentiviral Activation Particles (h)

sc-400167-LAChGene ActivationPuro, Blast, Hygro0
(0)

Notch1 CRISPR Activation Plasmid (m)

sc-421930-ACTmGene ActivationPuro, Blast, Hygro0
(0)

Notch1 Lentiviral Activation Particles (m)

sc-421930-LACmGene ActivationPuro, Blast, Hygro0
(0)

Notch 1 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Notch1 siRNA (h)

sc-36095hGene SilencingN/A
84
(0)

Notch1 siRNA (h2)

sc-44226hGene SilencingN/A
9
(0)

Notch1 shRNA Plasmid (h)

sc-36095-SHhGene SilencingPuromycin
84
(0)

Notch1 shRNA Plasmid (h2)

sc-44226-SHhGene SilencingPuromycin
9
(0)

Notch1 shRNA (h) Lentiviral Particles

sc-36095-VhGene SilencingPuromycin
84
(0)

Notch1 shRNA (h2) Lentiviral Particles

sc-44226-VhGene SilencingPuromycin
9
(0)

Notch1 siRNA (m)

sc-36096mGene SilencingN/A
7
(0)

Notch1 siRNA (m2)

sc-44315mGene SilencingN/A0
(0)

Notch1 shRNA Plasmid (m)

sc-36096-SHmGene SilencingPuromycin
7
(0)

Notch1 shRNA Plasmid (m2)

sc-44315-SHmGene SilencingPuromycin0
(0)

Notch1 shRNA (m) Lentiviral Particles

sc-36096-VmGene SilencingPuromycin
7
(0)

Notch1 shRNA (m2) Lentiviral Particles

sc-44315-VmGene SilencingPuromycin0
(0)

Notch1 siRNA (r)

sc-270189rGene SilencingN/A
12
(0)

Notch1 shRNA Plasmid (r)

sc-270189-SHrGene SilencingPuromycin
12
(0)

Notch1 shRNA (r) Lentiviral Particles

sc-270189-VrGene SilencingPuromycin
12
(0)