NOS1 Inhibitors
Santa Cruz Biotechnology now offers a broad range of NOS1 Inhibitors. Nitric oxide (NO) has a broad range of biological activities including cell signaling pathways in phylogenetically diverse species. Nitric oxide synthases (NOSs), the enzymes responsible for synthesis of NO, contain an N-terminal oxygenase domain and a C-terminal reductase domain. NOS1 (also designated ncNOS) is a constitutive Ca2+/CaM-dependent form of NOS, whose activity was first identified in neurons. NOS1 Inhibitors offered by Santa Cruz inhibit NOS1 and, in some cases, other cell signaling and nitric oxide synthesis related proteins. View detailed NOS1 Inhibitor specifications, including NOS1 Inhibitor CAS number, molecular weight, molecular formula and chemical structure, by clicking on the product name.
Items 51 to 54 of 54 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
2-Imino-4-methylpiperidine acetate | 165383-72-2 | sc-202402 sc-202402A | 5 mg 25 mg | $30.00 $90.00 | ||
2-Imino-4-methylpiperidine acetate exhibits a unique mechanism of action as a selective NOS1 modulator, primarily through its ability to form hydrogen bonds with key amino acid residues in the enzyme's active site. The piperidine ring contributes to its conformational flexibility, enhancing its interaction dynamics. Additionally, the acetate moiety facilitates solvation, optimizing its reactivity and influencing the kinetics of nitric oxide production, thereby impacting cellular signaling pathways. | ||||||
ARL 17477 dihydrochloride | 866914-87-6 | sc-361108 sc-361108A | 10 mg 50 mg | $129.00 $548.00 | ||
ARL 17477 dihydrochloride acts as a selective modulator of NOS1, characterized by its ability to engage in electrostatic interactions with charged residues within the enzyme's active site. The dihydrochloride form enhances solubility, promoting efficient diffusion across biological membranes. Its unique structural features allow for specific conformational adjustments, which fine-tune the enzyme's catalytic activity and influence downstream signaling cascades. | ||||||
Iromycin A | 213137-53-2 | sc-221763 sc-221763A | 500 µg 1 mg | $444.00 $638.00 | ||
Iromycin A functions as a selective modulator of NOS1, exhibiting unique binding dynamics through hydrophobic interactions with key amino acid residues. Its structural conformation facilitates a distinct orientation within the enzyme's active site, optimizing reaction kinetics. The compound's ability to stabilize intermediate states enhances its efficacy in modulating enzymatic activity, thereby influencing nitric oxide production and related signaling pathways. | ||||||
S-Ethyl N-Phenylisothiourea | 19801-34-4 | sc-208326 | 50 mg | $330.00 | ||
S-Ethyl N-Phenylisothiourea acts as a selective modulator of NOS1, characterized by its ability to form strong hydrogen bonds with specific residues in the enzyme's active site. This interaction alters the enzyme's conformational landscape, promoting a unique catalytic environment. The compound's steric properties influence substrate accessibility, while its electronic characteristics may affect electron transfer processes, ultimately impacting nitric oxide synthesis and related cellular signaling mechanisms. | ||||||