Date published: 2025-11-23

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NK-1R Antibodies

Santa Cruz Biotechnology offers a broad range of NK-1R monoclonal antibodies for various research applications. NK-1R monoclonal antibodies are suitable for western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). The neurokinin-1 receptor (NK-1R) plays a critical role in mediating the effects of substance P, a neuropeptide involved in pain perception, inflammation, and stress responses. Understanding NK-1R signaling pathways is essential for elucidating mechanisms underlying various physiological and pathological conditions, including anxiety, depression, and cancer. NK-1R research continues to advance our knowledge of neurological and inflammatory disorders. Investigating NK-1R expression patterns helps reveal its distribution across different tissues and cell types. NK-1R signaling studies provide insights into potential therapeutic targets for pain management and inflammatory conditions. NK-1R monoclonal antibodies from Santa Cruz Biotechnology enable researchers worldwide to advance scientific understanding of neurobiology and contribute to the development of innovative therapeutic strategies.

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NK-1R Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

NK-1R Antibody (D-11)

sc-365091mouse IgG1 κ325-407 (h)WB, IP, IF, IHC(P), ELISAm, r, h
13
(5)

NK-1R Antibody (F-3)

sc-514453mouse IgG2b κ374-391 (h)WB, IP, IF, ELISAm, r, h

new

(0)

NK-1R CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

NK-1R CRISPR/Cas9 KO Plasmid (h)

sc-401004hGene KnockoutGFP0
(0)

NK-1R HDR Plasmid (h)

sc-401004-HDRhHomology Directed RepairPuromycin0
(0)

NK-1R Double Nickase Plasmid (h)

sc-401004-NIChGene KnockoutPuromycin0
(0)

NK-1R Double Nickase Plasmid (h2)

sc-401004-NIC-2hGene KnockoutPuromycin0
(0)

NK-1R CRISPR/Cas9 KO Plasmid (m)

sc-423252mGene KnockoutGFP0
(0)

NK-1R HDR Plasmid (m)

sc-423252-HDRmHomology Directed RepairPuromycin0
(0)

NK-1R Double Nickase Plasmid (m)

sc-423252-NICmGene KnockoutPuromycin0
(0)

NK-1R Double Nickase Plasmid (m2)

sc-423252-NIC-2mGene KnockoutPuromycin0
(0)

NK-1R CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

NK-1R CRISPR Activation Plasmid (h)

sc-401004-ACThGene ActivationPuro, Blast, Hygro0
(0)

NK-1R CRISPR Activation Plasmid (h2)

sc-401004-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

NK-1R Lentiviral Activation Particles (h)

sc-401004-LAChGene ActivationPuro, Blast, Hygro0
(0)

NK-1R Lentiviral Activation Particles (h2)

sc-401004-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

NK-1R CRISPR Activation Plasmid (m)

sc-423252-ACTmGene ActivationPuro, Blast, Hygro0
(0)

NK-1R CRISPR Activation Plasmid (m2)

sc-423252-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

NK-1R Lentiviral Activation Particles (m)

sc-423252-LACmGene ActivationPuro, Blast, Hygro0
(0)

NK-1R Lentiviral Activation Particles (m2)

sc-423252-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

NK-1R siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

NK-1R siRNA (h)

sc-36069hGene SilencingN/A
2
(0)

NK-1R shRNA Plasmid (h)

sc-36069-SHhGene SilencingPuromycin
2
(0)

NK-1R shRNA (h) Lentiviral Particles

sc-36069-VhGene SilencingPuromycin
2
(0)

NK-1R siRNA (m)

sc-36070mGene SilencingN/A0
(0)

NK-1R shRNA Plasmid (m)

sc-36070-SHmGene SilencingPuromycin0
(0)

NK-1R shRNA (m) Lentiviral Particles

sc-36070-VmGene SilencingPuromycin0
(0)