Neuro D Activators
Common Neuro D Activators include, but are not limited to Forskolin CAS 66575-29-9, Valproic acid sodium salt CAS 1069-66-5, Sodium Butyrate CAS 156-54-7, Retinoic Acid, all trans CAS 302-79-4 and Lithium Chloride CAS 7447-41-8.
Neuro D Activators, a class of chemical compounds that modulate the activity or function of the Neuro D gene, also known as Neurogenic Differentiation 1. Neuro D is a transcription factor that plays a critical role in the development and differentiation of neurons. It belongs to the basic helix-loop-helix (bHLH) family of transcription factors and is involved in the regulation of genes that are essential for neuronal development, maturation, and function.
Activation of Neuro D through specific chemical compounds enhance its transcriptional activity, leading to the upregulation of target genes involved in neurogenesis and neuronal differentiation. The precise mechanism of action of Neuro D Activators would involve binding to Neuro D or its associated regulatory elements, leading to conformational changes that promote its binding to DNA and subsequent transcriptional activation. Such compounds might facilitate the recruitment of co-activators, modify chromatin structure, or enhance the stability of Neuro D protein, ultimately resulting in the increased expression of genes related to neuronal development and differentiation.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin activates adenylate cyclase, increasing cAMP levels and activating protein kinase A (PKA). This pathway can activate CREB, a transcription factor involved in neuronal plasticity, which could impact NeuroD expression through CREB-mediated pathways. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol modulates various signaling pathways, including those related to cell cycle regulation and gene expression. It might indirectly influence NeuroD expression through its effects on these pathways. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $87.00 | 9 | |
Valproic acid is an HDAC inhibitor that increases histone acetylation. By altering chromatin structure and gene expression, it could potentially promote an open chromatin state around the NeuroD gene promoter, facilitating transcription. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
Butyrate is an HDAC inhibitor that increases histone acetylation. Similar to valproic acid, it could affect NeuroD expression by promoting a more permissive chromatin structure for transcription. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic acid is known to promote neuronal differentiation. It could induce NeuroD expression as part of neuronal maturation and differentiation processes. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium can modulate signaling pathways, including those related to neurodevelopment. Its effects on NeuroD expression might be tied to its broader impact on neuronal signaling. | ||||||
Rosiglitazone | 122320-73-4 | sc-202795 sc-202795A sc-202795C sc-202795D sc-202795B | 25 mg 100 mg 500 mg 1 g 5 g | $120.00 $326.00 $634.00 $947.00 $1259.00 | 38 | |
Rosiglitazone activates PPARγ, which is involved in gene regulation. NeuroD might be indirectly impacted through PPARγ-mediated pathways. | ||||||