NDUFS7 Activators
NDUFS7 Activators encompass a diverse array of chemical compounds that indirectly contribute to the enhancement of NDUFS7 within the mitochondrial electron transport chain. Coenzyme Q10 directly supports the electron transfer process within complex I, where NDUFS7 is a key component, thus facilitating its activity. Nicotinamide adenine dinucleotide (NAD+), as a substrate, and Nicotinamide riboside, as a precursor to NAD+, boost the availability of essential substrates for the electron transport chain, thereby indirectly enhancing NDUFS7 function. The presence of Succinic acid further increases the demand for NADH oxidation, stimulating NDUFS7 activity. Mitoquinone mesylate and PQQ protect mitochondrial integrity by their antioxidant action, contributing to the preservation of NDUFS7's role in the complex. Additionally, the action of compounds like Spermidine, which promotes mitochondrial biogenesis, leads to an increased number of mitochondria containing NDUFS7, potentially upsurging its functional presence.
The activation of NDUFS7 is further facilitated by compounds that indirectly enhance the mitochondrial environment and substrate availability. L-Carnitine, by shuttling fatty acids into mitochondria, stimulates beta-oxidation, which leads to an increased production of acetyl-CoA, thus fueling the TCA cycle and enhancing NDUFS7's role in the electron transport chain. Alpha-lipoic acid, due to its role as a mitochondrial enzyme cofactor and its antioxidant properties, ensures an optimized redox state, which is crucial for the efficient operation of NDUFS7 within the electron transport chain. Resveratrol indirectly facilitates NDUFS7 function by activating sirtuins, which are known to enhance mitochondrial health. Trace elements such as Zinc sulfate and Copper (II) sulfate are essential for maintaining the structural and enzymatic aspects of mitochondrial complexes, thereby ensuring a smooth electron flow that indirectly supports NDUFS7's activity. Collectively, these activators, through their targeted effects on mitochondrial function and substrate availability, ensure the enhancement of NDUFS7-mediated electron transport without the need for direct interaction with the protein itself.
SEE ALSO...
Items 1 to 10 of 12 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Coenzyme Q10 | 303-98-0 | sc-205262 sc-205262A | 1 g 5 g | $70.00 $180.00 | 1 | |
Coenzyme Q10 participates in the electron transport chain within mitochondria. By shuttling electrons, it directly supports the function of complexes including the NDUFS7-containing complex I, thereby enhancing the functional activity of NDUFS7. | ||||||
Spermidine | 124-20-9 | sc-215900 sc-215900B sc-215900A | 1 g 25 g 5 g | $56.00 $595.00 $173.00 | ||
Spermidine induces autophagy and mitophagy, leading to the removal of dysfunctional mitochondria and the generation of new ones. This turnover is likely to increase the number of fully functional NDUFS7 proteins as part of the newly synthesized complex I. | ||||||
NAD+, Free Acid | 53-84-9 | sc-208084B sc-208084 sc-208084A sc-208084C sc-208084D sc-208084E sc-208084F | 1 g 5 g 10 g 25 g 100 g 1 kg 5 kg | $56.00 $186.00 $296.00 $655.00 $2550.00 $3500.00 $10500.00 | 4 | |
NAD+, as a substrate for complex I, is essential for its activation. Elevated levels of NAD+ can enhance the functional activity of NDUFS7 by increasing the substrate availability for the electron transport chain. | ||||||
Succinic acid | 110-15-6 | sc-212961B sc-212961 sc-212961A | 25 g 500 g 1 kg | $44.00 $74.00 $130.00 | ||
Succinic acid is a substrate for complex II of the electron transport chain. Its presence stimulates the downstream activity of complex I, where NDUFS7 resides, therefore indirectly enhancing NDUFS7 activity by increasing the demand for NADH oxidation. | ||||||
Mito-Q | 444890-41-9 | sc-507441 | 5 mg | $284.00 | ||
Mitoquinone mesylate acts as an antioxidant specifically targeting mitochondria. By reducing oxidative stress, it can preserve the integrity of mitochondrial complexes including complex I, potentially enhancing the activity of NDUFS7. | ||||||
Pyrroloquinoline quinone | 72909-34-3 | sc-210178 | 1 mg | $238.00 | ||
PQQ functions as a redox cofactor and antioxidant. It can indirectly enhance NDUFS7 activity by protecting mitochondrial complexes from oxidative damage, thus maintaining optimal electron transport chain function. | ||||||
Nicotinamide riboside | 1341-23-7 | sc-507345 | 10 mg | $411.00 | ||
Nicotinamide riboside is a precursor of NAD+ and could enhance NDUFS7 activity by increasing the pool of NAD+, thereby supporting complex I activity. | ||||||
L-Carnitine | 541-15-1 | sc-205727 sc-205727A sc-205727B sc-205727C | 1 g 5 g 100 g 250 g | $23.00 $33.00 $77.00 $175.00 | 3 | |
L-Carnitine facilitates the transport of fatty acids into mitochondria for beta-oxidation, leading to increased acetyl-CoA production, which then feeds into the TCA cycle and enhances the activity of the electron transport chain, including the NDUFS7 protein. | ||||||
α-Lipoic Acid | 1077-28-7 | sc-202032 sc-202032A sc-202032B sc-202032C sc-202032D | 5 g 10 g 250 g 500 g 1 kg | $68.00 $120.00 $208.00 $373.00 $702.00 | 3 | |
Alpha-lipoic acid serves as a cofactor for mitochondrial enzymes and also has antioxidant properties. It can indirectly support NDUFS7 activity by maintaining a favorable redox state within mitochondria and thus ensuring efficient electron transport. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol enhances the activity of sirtuins, which are known to positively influence mitochondrial function. Improved mitochondrial function can indirectly increase the activity of the electron transport chain and thus NDUFS7. | ||||||