MYH13 Inhibitors
Common MYH13 Inhibitors include, but are not limited to (±)-Blebbistatin CAS 674289-55-5, Y-27632 dihydrochloride CAS 129830-38-2, ML-9 CAS 105637-50-1, Jasplakinolide CAS 102396-24-7 and Cytochalasin C CAS 22144-76-9.
MYH13 inhibitors belong to a chemical class that targets the myosin heavy chain 13 (MYH13) protein. MYH13 is a motor protein that plays a crucial role in muscle contraction and movement by being a part of the sarcomere, the basic unit of muscle contraction. It is specifically found in certain types of muscle tissues, including smooth muscle cells in blood vessels and cardiac muscle cells in the heart.
Inhibiting MYH13 with these compounds may disrupt the normal function of muscle contraction, which could have implications for various physiological processes that depend on proper muscle function. By interfering with MYH13's motor activity, these inhibitors might affect the contractile properties of the muscles where MYH13 is expressed. Such inhibitors could be valuable tools for research aimed at understanding the molecular mechanisms of muscle contraction and the role of MYH13 in various muscle-related functions. This knowledge could contribute to a deeper understanding of muscle physiology and offer insights into muscle-related disorders where MYH13 dysregulation may play a role.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
(±)-Blebbistatin | 674289-55-5 | sc-203532B sc-203532 sc-203532A sc-203532C sc-203532D | 5 mg 10 mg 25 mg 50 mg 100 mg | $183.00 $313.00 $464.00 $942.00 $1723.00 | 7 | |
A small molecule inhibitor that could potentially interact with the motor domain of MYH13, affecting its ATPase activity and motor function. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
An inhibitor of the Arp2/3 complex that could indirectly affect MYH13 by modulating actin cytoskeleton organization. | ||||||
ML-9 | 105637-50-1 | sc-200519 sc-200519A sc-200519B sc-200519C | 10 mg 50 mg 100 mg 250 mg | $112.00 $449.00 $673.00 $1224.00 | 2 | |
Compounds targeting myosin light chain kinase could indirectly influence MYH13 by modulating actin-myosin interactions. | ||||||
Jasplakinolide | 102396-24-7 | sc-202191 sc-202191A | 50 µg 100 µg | $184.00 $305.00 | 59 | |
A natural compound that could potentially affect MYH13 through actin cytoskeleton dynamics and cellular processes. | ||||||
Cytochalasin C | 22144-76-9 | sc-202118 sc-202118A | 1 mg 5 mg | $122.00 $512.00 | 1 | |
A class of compounds that could impact MYH13 by affecting actin filament dynamics and cytoskeletal organization. | ||||||
Latrunculin A, Latrunculia magnifica | 76343-93-6 | sc-202691 sc-202691B | 100 µg 500 µg | $265.00 $815.00 | 36 | |
Compounds that might affect MYH13 through modulation of actin filament dynamics and cytoskeletal organization. | ||||||
Phalloidin | 17466-45-4 | sc-202763 | 1 mg | $234.00 | 33 | |
A toxin that could potentially interact with actin filaments and indirectly impact MYH13 function through cytoskeletal modulation. | ||||||
NSC-207895 | 58131-57-0 | sc-364550 sc-364550A | 5 mg 10 mg | $354.00 $666.00 | ||
A potential small molecule inhibitor that could affect MYH13 function and cellular processes by targeting its motor domain. | ||||||
Cytochalasin D | 22144-77-0 | sc-201442 sc-201442A | 1 mg 5 mg | $165.00 $486.00 | 64 | |
A class of compounds that could impact MYH13 by affecting actin filament dynamics and cytoskeletal organization. | ||||||
ML-7 hydrochloride | 110448-33-4 | sc-200557 sc-200557A | 10 mg 50 mg | $91.00 $267.00 | 13 | |
A kinase inhibitor that might impact MYH13 function by affecting phosphorylation events and actin-myosin interactions. | ||||||