MuRF1 Activators are a specialized class of chemical compounds that have garnered significant attention within the realm of molecular biology and cellular physiology. These compounds are primarily known for their unique ability to modulate the activity of Muscle RING Finger 1 (MuRF1), a critical protein involved in muscle homeostasis and regulation. MuRF1 is part of the E3 ubiquitin ligase family, and its primary function is to target specific proteins within muscle cells for degradation through the ubiquitin-proteasome pathway. This process plays a pivotal role in maintaining muscle protein turnover, ensuring the removal of damaged or unnecessary proteins, and regulating muscle mass. MuRF1 Activators, therefore, refer to a class of molecules that can enhance or stimulate the activity of MuRF1, potentially leading to increased protein degradation and, by extension, influencing muscle growth and maintenance.
The intricate regulation of MuRF1 activity by these activators has sparked significant interest in understanding their mechanisms of action and potential applications. Researchers have been investigating the molecular interactions between MuRF1 Activators and the MuRF1 protein, aiming to elucidate the pathways through which these compounds influence muscle protein turnover. This class of chemicals has the potential to shed light on fundamental processes governing muscle physiology and could have implications for a range of fields, including exercise science, aging research, and muscle-related disorders.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $91.00 $139.00 $374.00 | 36 | |
Induces murf1 expression via glucocorticoid receptor | ||||||
Angiotensin II, Human | 4474-91-3 | sc-363643 sc-363643A sc-363643B sc-363643C | 1 mg 5 mg 25 mg 100 mg | $51.00 $100.00 $310.00 $690.00 | 3 | |
Upregulates murf1 via MAPK signaling pathway | ||||||
Hydrogen Peroxide | 7722-84-1 | sc-203336 sc-203336A sc-203336B | 100 ml 500 ml 3.8 L | $31.00 $61.00 $95.00 | 28 | |
Induces oxidative stress leading to murf1 expression | ||||||
Lipopolysaccharide, E. coli O55:B5 | 93572-42-0 | sc-221855 sc-221855A sc-221855B sc-221855C | 10 mg 25 mg 100 mg 500 mg | $98.00 $171.00 $425.00 $1560.00 | 12 | |
Activates TLR4 signaling pathway for murf1 induction | ||||||
Adenosine 3′,5′-cyclic monophosphate | 60-92-4 | sc-217584 sc-217584A sc-217584B sc-217584C sc-217584D sc-217584E | 100 mg 250 mg 5 g 10 g 25 g 50 g | $116.00 $179.00 $265.00 $369.00 $629.00 $1150.00 | ||
Modulates cAMP/PKA pathway leading to murf1 expression | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Modulates RAR/RXR pathway to induce murf1 expression | ||||||